Make better projects decisions... FASTER!
Did
you know that Simulations Plus provides consulting services to numerous
pharmaceutical industry customers, including 4 of the top 5 companies?
Our team of highly-skilled scientists is available to assist with your drug discovery and development activities on a project-by-project basis. Our expertise, combined with our best-in-class software, provides you with modeling & simulation analysis that can greatly improve your decision-making process.
Some examples of how your company can benefit from our assistance:
With GastroPlus:
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Predict first-in-human (FIH) pharmacokinetic outcomes from available in vitro and preclinical data
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BENEFIT: Rank-order compounds based upon likely development promise
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Assess different formulation strategies to enhance the dissolution and/or absorption of your drug
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BENEFIT: Reduce the number of in vivo studies to achieve your target exposure levels
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Simulate a virtual clinical trial to generate a population outcome
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BENEFIT: Understand the likely sources of variation before going to the clinic
With DDDPlus:
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Design in vitro dissolution methods that better mimic in vivo release
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BENEFIT: Establish an IVIVC for possible biowaiver considerations
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Simulate dissolution profiles to evaluate new formulations
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BENEFIT: Reduce the number of experiments needed to achieve a target profile
With ADMET Predictor:
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Estimate various ADME-Tox properties from structure for a library of compounds
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BENEFIT: Screen compounds across a wide range of endpoints to identify the potential "losers" earlier
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Build custom QSAR models from your own data sets
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BENEFIT: Predict properties more accurately for your specific chemical series
With ClassPharmer:
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Classify large libraries into chemically similar groups
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BENEFIT: Provide an ideal starting point for local QSAR generation
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Perform de novo design of new molecules
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BENEFIT: Virtually create drugs with desired activity and ADME-Tox properties
If your organization does not have the time or resources to use our software directly, or if you need a fast turnaround on a particular project, our sophisticated analytical study support is the solution.
To begin discussing how we can help with your project, please contact:
Ms. Grace Fraczkiewicz
Team Leader, Consulting Services
661-723-7723 ext. 233
grace@simulations-plus.com
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