Jr. PBPK Modeler

Simulations Plus is a leading developer of modeling and simulation software, and a provider of consulting services. We support our pharmaceutical and biotechnology clients through drug discovery, development research, and regulatory submissions.

Leadership truly cares about maintaining a positive culture and for employee well-being. We offer fully remote work, flexible schedules, unlimited vacation along with free medical premiums, stock options, bonus potential, and more!

The Jr. PBPK Modeler will perform PBBM/PBPK modeling and simulation to address objectives with client projects such as FIH predictions, formulation design/optimization, population simulations, and DDI predictions.

Division: Simulations

Department: Life Sciences

Location: This position can be 100% remote or hybrid near Lancaster, CA 

Job Responsibilities:

  • Support research collaboration projects with industry partners and regulatory agencies
  • Review, compile, and document data from various sources
  • Build and validate PBBM/PBPK models
  • Contribute to the advancement of scientific algorithms and approaches
  • Serve as technical lead on PBBM/PBPK modeling and simulation client projects
  • Write study proposals, modeling reports, white papers, and journal publications while clearly describing model development and validation
  • Assist in the testing of software products
  • Help in the preparation of training materials
  • Attend and present at scientific conferences
  • Other duties as assigned 


  • Hands-on knowledge of PBBM/PBPK modeling applications from preclinical development to clinical pharmacology
  • Excellent verbal and written communication skills
  • Fluent in multiple languages a plus
  • Maintain a positive attitude while interacting with colleagues and clients
  • Build and strengthen strategic partnerships across the industry
  • Must be able to multitask and have strong organizational skills
  • Self-motivated with ability to work with minimal supervision
  • Minimal travel required up to 10%


  • Masters in pharmaceutical science, biostatistics, biomedical engineering, chemistry, or related field
  • PhD in pharmaceutical science, biostatistics, biomedical engineering, chemistry, or related field preferred

Find out more about how amazing it is to work at Simulations Plus by visiting www.simulations-plus.com/career-center and apply today!

Base Pay Range: 90k – 120k USD per year