Senior Director, Pharmacometrics

Simulations Plus is a leading developer of modeling and simulation software, and a provider of consulting services. We support our pharmaceutical and biotechnology clients through drug discovery, development research, and regulatory submissions.

Leadership truly cares about maintaining a positive culture and for employee well-being. We offer fully remote work, flexible schedules, unlimited vacation along with free medical premiums, stock options, bonus potential, and more!

We are looking for a Senior Director, Pharmacometrics to lead multi-disciplinary project teams through the successful completion of client goals.

Division: Cognigen

Department: Pharmacometric Services

Location: This position can be 100% remote or hybrid near Buffalo, NY

Job Responsibilities:

  • Independently develop and evaluate more complex models and simulations
  • Lead, manage, and work with multidisciplinary project teams to successfully support client requests
  • Build partnerships with clients; provide strategic input and advice
  • Provide strategic direction regarding the integration of modeling and simulation results and findings
  • Assist in teaching workshops and providing training
  • Mentor junior-level scientists; may supervise assigned scientists
  • Promote software and consulting service offerings; may assist in developing proposals and work scopes
  • Serve as main point of contact for assigned clients and projects
  • Consult with clients on study design through development and evaluation of models
  • Provide valuable insight into the optimal use of modeling and simulation in drug development programs
  • Clearly communicate and present modeling and simulation results to clients
  • Use state-of-the-art software to develop, evaluate and apply PK, PK/PD and exposure-response models
  • Formulate pharmacometric data analysis plans, ensuring appropriateness of methods for data handling and analysis and compliance with current global regulatory guidance
  • Perform model-based simulations to address critical development questions
  • Collaborate effectively in cross-functional teams to deliver analysis results
  • Write pharmacometric reports and regulatory documents
  • Utilize internal resources to meet project timelines and budgets
  • Share scientific knowledge and skills with other staff members
  • Lead the development of proposals, reports, manuscripts and/or white papers
  • Lead or contribute to the development of standard processes and methods
  • Teach workshops and develop new training material
  • Serve as a role model for the advancement of consulting services

Education and Experience:

  • PhD in pharmacometrics, PK/PD, pharmaceutics, pharmacology, engineering, or related field preferred
  • Masters in pharmacometrics or statistics will be considered
  • Proficiency in Monolix, NONMEM, and R
  • Population PK and PK/PD modeling experience
  • Professional experience in applying Pharmacometrics  preferred

Find out more about how amazing it is to work at Simulations Plus by visiting and apply today!

Base Pay Range: 175k – 200k USD per year