
4th Asian Pharmacometrics Network Symposium
November 9 - November 10
Malaysia
The theme for the 4th APN symposium 2022 is “Application of Pharmacometrics in Drug Development and Clinical Practice”.
Join our Lixoft team for a FREE 2-day pre-conference workshop.
Development of population pharmacokinetic models with Monolix™
Monday 7th November, 2:30-5:30pm Malaysian Time
-
- Theoretical recap on the population approach
- Data formatting and data visualization
- Setup of a Monolix run (data definition, structural model, statistical model)
- Estimation tasks and model diagnostic with the plots and statistical tests
- Stepwise development of the structural model (using the model libraries)
- Stepwise development of the statistical model, including covariate search
- Presentation of the hands-on exercise
Development of population PPDK models with Monolix and simulation of a new scenarios in Simulx™
Tuesday 8th November, 2:30-5:30pm Malaysian Time
- Presentation of the hands-on solution
- Mlxtran language for custom model writing
- PKPD model development strategies (sequential, joint)
- Export of a Monolix run to Simulx
- Definition of the simulation of new scenarios, in particular, new dosing regimens
- Post-processing of simulation results
- Presentation of the hands-on exercise