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AAPS 2020 PharmSci 360

October 26, 2020 - November 5, 2020

AAPS 2020 PharmSci 360

October 26 – November 5

Rapid Fire Sessions: 

Using the Connect360 tool you can schedule meetings with any of our presenters and moderators throughout the event!

Model Informed Drug Development: 2020 and Beyond
Tuesday, October 27, 3:30 – 4:30 PM EST
Kyunghee Yang – Senior Scientist at DILIsym Services Inc., a Simulations Plus company

Quantitative Systems Toxicology Modeling of Drug-induced Liver Injury & Adaptation
Wednesday, October 28, 2020 @ 9:30 – 9:45 AM EST
Kyunghee Yang – Senior Scientist at DILIsym Services Inc., a Simulations Plus company

Clinical Pharmacology Driving Innovative Trial Design
Tuesday, November 3, 2020 @ 9:00-9:45 AM EST
Kevin Dykstra – Vice President, Consulting Services at Cognigen Corporation, a Simulations Plus company

Hepatotoxicity of Compound V Evaluated with Quantitative Systems Toxicology
Wednesday, November 4, 2020 @ 4:00 – 4:15 PM EST
Vinal V. Lakhani – Scientist I at DILIsym Services Inc., a Simulations Plus company

PharmSci360 Poster Presentations:

Physiologically Based Pharmacokinetic Modeling of Oxybate: The Role of Counter-ions in Gastrointestinal Absorption
Michael Bolger – Founding Scientist at Simulations Plus
William van Osdol – Principal Scientist at Simulations Plus

PBBM Analysis of the In Vivo Behavior of Amorphous Solid Dispersions Based on Water-Soluble versus Water-Insoluble Carriers: A Fenofibrate Case Study
(presented by the University of Toronto )
Jasmina Novakovic – Principal Scientist, Simulations Plus

*Best Abstract Award Winner: PBBM Analysis of the In Vivo Behavior of Amorphous Solid Dispersions Based on Water-Soluble versus Water-Insoluble Carriers: A Fenofibrate Case Study

*Best Abstract Award Winner: Physiologically Based Pharmacokinetic Modeling of Oxybate: The Role of Counter-ions in Gastrointestinal Absorption

Physiologically-Based Pharmacokinetic Model to Describe the Pharmacokinetics of Crushed Morphine Sulfate and Naltrexone Hydrochloride Extended-Release Capsules with Abuse Deterrent Properties

Modeling the Impact of Amorphous Drug-Polymer Colloids on the Absorption of Poorly Water Soluble Drugs

Pharmacokinetic Profile and Physiologically Based Pharmacokinetic Modeling of Matrine in Healthy Human Plasma and Saliva

Quantitative Systems Toxicology Identifies the Mechanism and Data Gaps for Evaluating the Hepatotoxicity of Compound V

Quantitative Systems Toxicology (DILIsym) Modeling of the Acetaminophen (Paracetamol) Mode of Action (MOA) Pathway for Hepatotoxicity Supports that Acetaminophen Is Not a Carcinogenic Hazard in Humans

Quantitative Systems Toxicology Modeling Using DILIsym Suggests That Drug-Induced Liver Injury Can Be Enhanced by Co-administered Drugs and Mitigated by Mitochondrial Biogenesis

Application of Minimal Physiologically Based Pharmacokinetic Model for Insulin: A Population Analysis

Hybrid CFD-PBPK Model for Prediction of Systemic PK Following Nasal Insufflation of Milled Oxycodone Hydrochloride Extended-Release Tablets

Applying Computational Prediction of Biorelevant Solubility in Dispersions of Self-Emulsifying Lipid-Based Formulations to Predict Dose Number

Simulations Plus AAPS Virtual Booth VB1921 will be hosted by:
Arlene Padron 

Dan O’Connor 

Cherylann Iagatta 

Learn more here

Learn more about APX

Learn more about DSX

Details

Start:
October 26, 2020
End:
November 5, 2020
Website:
https://www.eventscribe.com/2020/PharmSci360/

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