Dr. Jérôme Kalifa is an applied mathematician and high-tech entrepreneur. Jérôme Kalifa joined the Monolix project in 2010 to create a company based on the breakthrough technologies created at Inria and co-founded Lixoft with several key members of the Monolix team. Prior to Lixoft, Jérôme Kalifa co-founded Let It Wave (Paris, France, and Palo Alto, USA) in 2001, a startup dedicated to digital image processing spun off from the Center for Applied Mathematics at Ecole Polytechnique (Paris, France). Jérôme was a key contributor to Let It Wave’s technologies, and developed Let It Wave’s business in several industrial markets and overseas while managing its most complex product development programs. Let It Wave had grown to 40 employees when it was acquired by Zoran Semiconductors in 2008, after raising venture capital in early 2006. Jérôme Kalifa has a Ph.D. in applied mathematics from Ecole Polytechnique, Paris, France in 1999, and did a post-doc at Columbia University (New York, USA) on biomedical image processing, from 1999 to 2001. He is the author of numerous research papers, patents, and software applications, in the areas of digital signal, image & video processing, seismic data processing, wavelet analysis, inverse problems, and non-parametric statistical estimation.