KIWI™

Cloud-based pharmacometric communication
platform

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Bringing your user experience to a new level through efficient, decisive model building and co-worker collaboration

KIWI™ 4 continues to bring user experience to a new level through efficient, decisive management of your population PK modeling projects and co-worker collaboration.

Share your share suite of customized diagnostic plots with your co-worker or use them on your next project.

Visualizekiwi multi visualize gof

Visualize diagnostic plots and parameters for all candidate models in one view.

Often there are multiple candidate models to review in order to select the one final model or the model that will direct you in a different path of model building. Evaluating the diagnostic plots and parameter and variance estimates is critical in decision making, but it is often confusing opening different graphs at one time by cutting and pasting into a word document or powerpoint presentation.

Formats / Labels

Fully customized formatting and labeling within KIWI.

KIWI 4 has customized format and label collections that can be used throughout a project or across different projects.  This provides the modeler more control over the appearance of their graphs and tables. And these high quality graphs can be downloaded individually or as a group for direct import into a presentation or regulatory document. All formatted, all validated.  Significantly reduces your time spent in preparing presentations and regulatory documents.

KIWI multi visualize delta

Profiles, unique to KIWI, is a user interface to generate customized diagnostic, VPC, or bootstrap graphs with the ability to stratify by covariate, dose groups, etc.. A modeler can create as many profiles as desired. The Profiles can now be easily shared across projects for a single user or shared with co-workers, saving considerable time.

 

 

What are providing with KIWI™?

KIWI is a cloud-based web application that was developed to efficiently organize, process, maintain, and communicate the volume of data and results generated by pharmacologists and scientists over the duration of a drug development program. The validated workflow and tools within KIWI promote traceability and reproducibility of results.

Leveraging our 20+ years of experience in providing an architecture supporting population PK/PD modeling and simulation efforts, we have developed KIWI as a secure, validated, enterprise-scale environment, enabling global teams to collaborate on model-based decision making.

Speed and agility is more important than ever as the demand for M&S increases. KIWI allows you to easily select and compare parameters estimates and diagnostic plots across multiple candidate models in one view to make decisions quickly and confidently, and delivers high quality graphs to inform team decision making and put in regulatory documents – all formatted, all validated!

In KIWI, all the plots appear side by side in one view, and with a click of a button the parameter and variance estimates for the same models appear. The models can be easily switched up on the fly. Your teams will love being able to more easily distinguish between models by reviewing graphs and parameter estimates simultaneously and having engaging discussions where decisions are made!

What's new in KIWI™ 4?

This Pharmacometric Communication and Collaboration Platform includes:

Model Wizard

  • This new module will allow users to easily create NONMEM, mrgsolve, and Berkeley Madonna code from a library of template PK and PK/PD models.
    The wizard will provide many fields for intuitive point-and-click selection of model settings along with a general editing area where template code can be modified.

Workbench

  • New functionality will automatically generate univariate control streams for stepwise covariate analysis.
  • The file editor will now allow users to open 2 files simultaneously for side-by-side viewing and editing.

Manage

  • Functionality for automated and custom addition of flags has been introduced to document exploratory analysis results obtained on data files (similar to that provided for NONMEM and Perl-speaks-NONMEM runs).

Explore

  • A new setting will allow users to customize which dataset values are interpreted by KIWI as missing data.

Data Repository

  • An improved Browse Files view that adds information about each uploaded file.
  • An improved Browse Explorer view that displays a count of uploaded files within a folder structure.
  • An improved Staging Area view that displays a column showing when a file was last modified. This column will have additional functionality allowing a filtering of rows that are visible.
  • Downloading multiple files at once will be allowed.
  • A complete view of all uploaded files within an entire storage component (drug/project/study) will be provided.
  • Administrators will have the ability to rename a drug/project/study folder.

 

  

Just what you would expect from a fully integrated population PK/PD model management and communication platform.

See What KIWI Can Offer Your Team