Leverage the science, models and refined algorithms GastroPlus users rely on—now with a more intuitive interface, faster processing, time-saving reusable assets, and streamlined workflows for faster and easier PBPK modeling and simulation.
GastroPlus X.2
is here
is here
Other PBPK Platforms vs. GPX.2
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Functionality
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Others
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GastroPlus
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Includes animal models
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Rat, dog, mouse, monkey
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Rat, dog, mouse, monkey, rabbit, minipig
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Includes multiple human populations
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Includes pediatric and geriatric populations
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Incorporates drug product batch dissolution data into a PBBM model (P-PSD)
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Minimal or full absorption modeling
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Offers cutting-edge virtual replicate BE study designs
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Unlimited victim/perpetrator compounds for polypharmacy DDI simulations
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Offers in-platform data visualization
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Can run and visualize multiple simulations in one run
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Extends capabilities with custom R/Python code for complex reporting, plotting & functionality
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Includes full equation guide
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Offers integrated AI/ML property prediction for ADME endpoints
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Provides real-time model guidance using AI and expert decision trees
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AI-assisted data extraction capabilities from publications, reports, and more
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Automates workflows using REST API
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Allows unlimited forms for formulation design
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Offers integrated noncompartmental PK analysis
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Unlimited metabolite tracking around the body
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Allows pre-simulation set-up check
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Customizable licensing to support company needs
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Accelerate model building by saving projects as templates or using included ready-made templates
Dose multiple compounds to multiple virtual patient populations at once
Improve your understanding through high-level summaries and deep dive views of your predictions
Improved accuracy in the #1-rated absorption model with enhanced capabilities validated in collaboration with the FDA and pharmaceutical companies
Upgraded trial designs and robust statistical engines to support your regulatory interactions
Get real-time model guidance and answers to technical questions with your virtual embedded expert and AI-powered tools
Minimize error and improve efficiency by building, executing & manipulating GPX projects and accessing external computational engines
Open science support provides full transparency to the model structures that drive your predictions
Flexible schedules cover all your study scenarios
FAQ
Frequently Asked Questions
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How can I access GPX.2?
Download and installation is now available for all existing GastroPlus clients. If you are a current customer and have questions, reach out to your Simulations Plus account manager. If you are not yet a client but would like to learn more about licensing our software, you can schedule a software demo here.
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My IT department has technical questions about installing GPX.2. How can I get them answers?
We recognize that understanding the cybersecurity and technical requirements of a new software platform is a critical component of IT’s role within an organization. Please have someone from your IT team watch our on-demand webinar.
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What training is available to get my team up to speed?
We have multiple in-person and online workshops available for registration. You can also request an in-person training for your organization by contacting Peter Kilford.
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How do I get the most out of GastroPlus?
To maximize your use of GastroPlus, we highly recommend a few options:
- If you’re relatively new to GastroPlus, review our GPX Tutorial Series. Our experts will explain how to navigate the interface and perform a variety of tasks.
- If you are a more experienced GastroPlus user and want in-depth instruction, consider registering for one of our focused on-demand courses. These can be taken at your convenience.
- Join the GastroPlus User Group and learn from your industry peers.
- Sign up to receive our GastroPlus newsletter, which will provide sneak peeks at upcoming software releases, webinars, and in-person events.
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What is new in GPX.2?
Check out all the new features and enhancements in the Release Notes.
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My quality management team would like to go through the qualification process. Any shortcuts you can point me to?
Your company’s GPX installation directory contains a validation suite – at no extra cost to you! This is an easy, streamlined option to run a series of automated simulations to ensure your installed version is producing the correct results.