PBPK Modeling Essentials: From IV Disposition to Oral Absorption in GastroPlus
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This pre-conference workshop is for beginner modelers attending the International PBPK Conference who want to learn the basics of PBPK modeling in GastroPlus (version 10.2). Over two sessions you’ll learn how to estimate an API distribution and elimination following intravenous administration and setup basics parameters influencing absorption. More than a software tutorial, this course gives you the framework, skills and mindset to develop your PBPK models supporting internal decision processes and regulatory decisions.

What You’ll Learn

  1. Building PBPK Models in GastroPlus®: Distribution and Elimination Basics
  2. Modeling absorption in GastroPlus®: Practical Tips and Key Challenges

Key Takeaways

  • Understand the core principles of PBPK modeling and how they are implemented in GastroPlus® (v10.2)
  • Gain hands-on experience building IV PBPK models to characterize both drug distribution and elimination
  • Understand the key API-related and formulation-related factors driving oral absorption
  • Develop practical skills to set up, troubleshoot, and refine absorption models in GastroPlus®
  • Recognize common challenges and pitfalls in PBPK model development and how to address them
  • Build a structured modeling workflow and mindset applicable to internal decision-making and regulatory support

Event Timing:

DAY 1: April 21, 01:30 PM – 05:30 PM CEST

DAY 2: April 22, 09:00 AM – 12:30 PM CEST