Simulations Plus Announces Collaboration with Lonza and U.S. FDA to Advance Predictive Frameworks for Complex Oral Drug Products

Simulations Plus Announces Collaboration with Lonza and U.S. FDA to Advance Predictive Frameworks for Complex Oral Drug Products

Keywords: amorphous solid dispersion (ASD) drug products, drug absorption, gastroplus, in vitro, Lonza, mechanistic modeling, Physiologically Based Biopharmaceutics Modeling (PBBM), U.S. Food and Drug Administration (FDA)
Software: GastroPlus®

Mechanistic modeling approach and experimental integration designed to improve early risk identification, strengthen regulatory confidence, and expand AI-enabled workflows connecting data to decision-making

Simulations Plus Announces Extensions of U.S. FDA and NIEHS Research Collaborations

Simulations Plus Announces Extensions of U.S. FDA and NIEHS Research Collaborations

Keywords: FDA, food and chemical safety assessmets, in silico, model-informed drug development, New Approach Methodologies (NAMs), U.S. Food and Drug Administration (FDA), U.S. National Institute of Environmental Health Sciences (NIEHS)

Extended projects support ongoing research into computational approaches and new approach methodologies for food and chemical safety assessment

Simulations Plus and the Institute of Medical Biology of the Polish Academy of Sciences Partnership Announces Results in Validation of ADMET Predictor® Models with Enhanced AI Drug Design

Simulations Plus and the Institute of Medical Biology of the Polish Academy of Sciences Partnership Announces Results in Validation of ADMET Predictor® Models with Enhanced AI Drug Design

Keywords: admet predictor, AIDD, American Chemical Society (ACS) Medical Chemistry Letters., artificial intelligence-driven drug design (AIDD), cheminformatics
Software: ADMET Predictor®
Division: Cheminformatics

Researchers found 70% of compounds designed in ADMET Predictor demonstrated significant activity during in vitro testing