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Latest Journal Articles
Lowly-buffered biorelevant dissolution testing is not necessarily biopredictive of human bioequivalence study outcome: Relationship between dissolution and pharmacokinetics
  • January 20, 2023
  • Journal Articles
Lowly-buffered biorelevant dissolution testing is not necessarily biopredictive of human…
Matsui K, Nakamichi K, Nakatani M, Yoshida H, Yamashita S, Yokota S
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Investigating bile acid-mediated cholestatic drug-induced liver injury using a mechanistic model of multidrug resistance protein 3 (MDR3) inhibition
  • January 17, 2023
  • Journal Articles
Investigating bile acid-mediated cholestatic drug-induced liver injury using a mechanistic…
Beaudoin J, Yang K, Adiwidjaja J, Taneja G, Watkins PB, Siler SQ, Howell BA, Woodhead JL
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Physiologically Based Biopharmaceutics Modeling of Food Effect for Basmisanil: A Retrospective Case Study of the Utility for Formulation Bridging
  • January 5, 2023
  • Journal Articles
Physiologically Based Biopharmaceutics Modeling of Food Effect for Basmisanil: A…
Belubbi T, Bassani D, Stillhart C, Parrott N
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Regulatory utility of physiologically based pharmacokinetic modeling for assessing food impact in bioequivalence studies: A workshop summary report
  • January 3, 2023
  • Journal Articles
Regulatory utility of physiologically based pharmacokinetic modeling for assessing food…
Al Shoyaib A, Emami Riedmaier A, Kumar A, Roy P, Parrott NJ, Fang L, Tampal N, Yang Y, Jereb R, Zhao L, Wu F
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Structure-activity relationship read-across and transcriptomics for branched carboxylic acids
  • December 30, 2022
  • Journal Articles
Structure-activity relationship read-across and transcriptomics for branched carboxylic acids
Wu S, Ellison C, Naciff J, Karb M, Obringer C, Yan G, Shan Y, Smith A, Wang X, Daston GP
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