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        GastroPlus®
        PBBM/PBPK
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        PBBM / PBPK modeling & simulation software package which simulates all major dosing routes and drug-drug interactions (DDIs) in virtual human & animal population groups.

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      • MonolixSuite™
        MonolixSuite™
        PK/PD
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        Easy, fast, and powerful tool for parameter estimation in non-linear mixed effect models, model diagnosis and assessment, and advanced graphical representation.

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    • ADMET Predictor®
      • ADMET Predictor®
        ADMET Predictor®
        ADMET/ML
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        Flagship machine learning platform for ADMET modeling with extended capabilities for data analysis, metabolism prediction, high-throughput pharmacokinetic simulation (HTPK), and AI-driven drug design.

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      • Modules

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    • DILIsym®
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        DILIsym
        QST
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        Quantitative Systems Toxicology (QST) software designed to be used during drug development to provide deeper insight into the mechanisms responsible for observed drug-induced liver injury (DILI) responses.

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    • DDDPlus™
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        DDDPlus™
        PBBM/PBPK
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        A mechanistic simulation engine for the in vitro dissolution experiment that predicts in vitro disintegration and dissolution of pharmaceutical dosage forms.

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    • NAFLDsym®
      • NAFLDsym®
        NAFLDsym®
        QSP
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        Quantitative Systems Pharmacology (QSP) software for mechanistic mathematical modeling of nonalcoholic fatty liver disease (NAFLD.)

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    • MembranePlus™
      • MembranePlus™
        MembranePlus™
        PBBM/PBPK
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        A detailed modeling & simulation program for in vitro metabolism & transport studies.

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      • PKanalix™
        PKanalix™
        PK/PD
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        Graphical and interactive software for non-compartmental and compartmental analysis.

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    • Simulx™
      • Simulx™
        Simulx™
        PK/PD
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        A powerful and flexible simulator for clinical trial pharmacometrics.

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    • IPFsym®
      • IPFsym®
        IPFsym®
        QSP
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        IPFsym®

        Quantitative Systems Pharmacology (QSP) software providing the ability to predict the efficacy of drugs being developed to treat idiopathic pulmonary fibrosis (IPF.)

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    • ILDsym™
      • ILDsym™
        ILDsym™
        QSP
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        ILDsym™

        Quantitative Systems Pharmacology (QSP) software for mechanistic mathematical modeling of interstitial lung disease (ILD) associated with system sclerosis (SSc.)

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    • RENAsym®
      • RENAsym®
        RENAsym®
        QST
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        RENAsym®

        Quantitative Systems Toxicology (QST) software for predicting and understanding drug-induced kidney injury.

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        • RENAsym, a QST Model to Predict Drug-Induced Kidney Injury
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    • MedChem Designer™
      • MedChem Designer™
        MedChem Designer™
        ADMET/ML
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        MedChem Designer™

        FREE chemical sketching software tool which combines innovative molecule drawing features.

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        • Download for Free
        • Free 30-Day Evaluation of ADMET Predictor®

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      • Custom QSP tools for your application
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        Custom QSP software for predicting efficacy & guiding design.

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  • July 1, 1994
  • Journal Articles

Alternatives to intravenous tetracycline hydrochloride for malignant pleural effusions

Keywords: administration & dosage, Bleomycin, comparative study, Doxycycline, humans, infusions, intravenous, Malignant, methods, P.H.S., pharmacists, Pleural Effusion, Pleurodesis, questionnaires, research support, supply & distribution, t, Tetracycline, U.S.Gov&rsquo
Division: Cognigen
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