Azole Antifungals: Physiologically-Based Pharmacokinetic (PBPK) Modeling and Prediction of Drug-drug Interactions (DDIs)

Authors: Fraczkiewicz G, Lukacova V, Parrott N, Bolger MB, Woltosz WS
Conference: Rosenon
Keywords: azole antifungals, drug-drug interactions (DDIs), Physiologically based pharmacokinetic (PBPK) modeling
Software: GastroPlus®
Division: Simulations Plus

Purpose

Develop PBPK models for azole antifungals for prediction of DOis.

By Grace Fraczkiewicz, Viera Lukacova, Michael B Bolger, Walt S Woltosz