Establishment of physiologically based pharmacokinetic model of atorvastatin

Authors: , Zhu L, Zhang Y, Yang J
Publication: Chinese J Hospital Pharmacy
Software: GastroPlus®

Objective

To develop aphysiologically based pharmacokinetic model of atorvastatin for predicting tissue distribution features of atorvastatin in body under healthy conditions,provide a basis for optimal treatment of atorvastatin.