Establishment of physiologically based pharmacokinetic model of atorvastatin
Keywords: atorvastatin physiologically based pharmacokinetic, model tissue distributionSoftware: GastroPlus®Publication: Chinese J Hospital Pharmacy
Objective
To develop aphysiologically based pharmacokinetic model of atorvastatin for predicting tissue distribution features of atorvastatin in body under healthy conditions,provide a basis for optimal treatment of atorvastatin.