Game Changing: The Latest Developments in the Machine Learning/ PBPK/QST Modeling Space

Authors: DiBella J, Howell BA
Conference: SOT
Software: DILIsym®, GastroPlus®

GastroPlus PBPK Models in Combination with DILIsym SimPops 13
• GastroPlus users build PBPK models within GastroPlus
• The “DILIsym” simulation mode in v9.7 allows users to select a mapping of GastroPlus outputs to DILIsym PK inputs
• Easy, simple-to-use template automatically generated for GastroPlus users to import into drug distributionDILIsym and drive simulations!

By Brett A Howell & John DiBella

Society of Toxicology 58th Annual Meeting and ToxExpo, March 10-14, 2019, Baltimore, MD