HTPK: A bridge to Early Development

Authors: Jamois E
Conference: SLP MIDD+
Keywords: discovery, DMPK, HTPK, PK assessment, SLP MIDD+ Virtual Conference, SLP2021MIDD
Software: ADMET Predictor®
Division: Simulations Plus

High-Throughput PK – Vision

  • Develop a simplified early PK assessment tool for non DMPK experts
  • Provide dose and time-dependent modeling capabilities
  • Avoid the need to input experimental values but allow their use if available
  • Identify potential development issues as early as possible, even before compounds are synthesized

By Eric Jamois

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Presented at SLP MIDD+ Virtual Conference March 3-4, 2021