October 2022 GastroPlus Newsletter

Software: GastroPlus®, ILDsym™
Division: PBPK


Breaking News! The new version of GP (version 9.8.3) is now available for download. Please check your inbox for download instructions. If have not yet received a message from Citrix ShareFile inviting you to connect, please contact our licensing department: licensing@simulations-plus.com.

We’ll be in person next week at AAPS PharmSci 360 (Oct. 16-19) in Boston. If you are attending, please join us for good food, drinks, and a bit of fun at our 18th Annual Simulations Plus Forum (remember the armadillo races in San Antonio?) on Tuesday, October 18 from 6:00 to 9:00 PM EST at the Westin Boston Seaport.  RSVP early to earn 2 raffle tickets! RSVP to arlene.padron@simulations-plus.com.

Don’t forget to stop by and see us at booth #1219. Try your luck at our Virtual Reality Home Run Derby, Plank Walk game, or sticker matching game to win a cool T-shirt.

  • Can’t miss presentations
    • Keynote Session Sandra Suarez-Sharp, Vice President of Regulatory Affairs will present “From Preclinical to Clinical Drug Product Development- A Path for Smooth Transition” on Oct. 18, from 1:30 – 2:30 pm EST.
    • Rapid Fire Session: Model Informed Drug Development (MIDD): Role in Dose Selection, Vulnerable Populations, and Biowaivers (CE) – Application of Modeling and Simulation in Long-Acting Injectable Product Development
      Speaker: Chief Scientific Officer, Viera Lukacova on Oct. 18 from 3:15 PM – 3:30 pm EST
  • Posters
    • Establishment of preclinical mechanistic in vitro-in vivo correlations for long-acting injectable suspensions
      Presented by: Daniela SilvaOct. 17 at 10:30 am EST
    • ILDsym successfully simulates SSc-ILD pathophysiology and inter-patient variability
      Presented by: Zackary KenzOct. 17 at 1:30 pm EST
    • Use of Quantitative Systems Toxicology (QST) to Identify Potential Intrinsic Mechanisms of Toxicity
      Presented by: Christina BattistaOct. 17 at 3:30 pm EST
    • Physiologically Based Pharmacokinetic (PBPK) Modeling of Rifampicin and Its Application for Drug-Drug Interaction with Midazolam in Adults
      Presented by: Suvarchala AvvariOct. 19 at 9:30 am EST
    • Clinical Ocular Exposure Extrapolation Using PBPK Modeling and Simulation: Gatifloxacin Solution Case Study
      Presented by: Scientist II, Farah Al QaraghuliOct. 19 at 12:30 pm EST

We continue to expand our workshop course offerings as well. This is a great way to introduce new users to the platform or refresh your skills:

Lastly, we continue to grow and add world-class scientists to our team… more to come with announcements later this month.

Please don’t forget to stop by the booth if you are in Boston next week and of course, let me know how we may help you and your teams to continue to advance the science of discovery.

By Dan O’ Connor