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        GastroPlus®
        PBBM/PBPK
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        PBBM / PBPK modeling & simulation software package which simulates all major dosing routes and drug-drug interactions (DDIs) in virtual human & animal population groups.

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        MonolixSuite™
        PK/PD
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        Easy, fast, and powerful tool for parameter estimation in non-linear mixed effect models, model diagnosis and assessment, and advanced graphical representation.

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        ADMET Predictor®
        AIDD/ML
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        Flagship machine learning platform for ADMET modeling with extended capabilities for data analysis, metabolism prediction, high-throughput pharmacokinetic simulation (HTPK), and AI-driven drug design.

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        Quantitative Systems Toxicology (QST) software designed to be used during drug development to provide deeper insight into the mechanisms responsible for observed drug-induced liver injury (DILI) responses.

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        A mechanistic simulation engine for the in vitro dissolution experiment that predicts in vitro disintegration and dissolution of pharmaceutical dosage forms.

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        Quantitative Systems Pharmacology (QSP) software for mechanistic mathematical modeling of nonalcoholic fatty liver disease (NAFLD.)

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        Graphical and interactive software for non-compartmental and compartmental analysis.

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        IPFsym®
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        IPFsym®

        Quantitative Systems Pharmacology (QSP) software providing the ability to predict the efficacy of drugs being developed to treat idiopathic pulmonary fibrosis (IPF.)

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        ILDsym®

        Quantitative Systems Pharmacology (QSP) software for mechanistic mathematical modeling of interstitial lung disease (ILD) associated with system sclerosis (SSc.)

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        RENAsym®

        Quantitative Systems Toxicology (QST) software for predicting and understanding drug-induced kidney injury.

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        MedChem Designer™
        ADMET/ML
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        MedChem Designer™

        FREE chemical sketching software tool which combines innovative molecule drawing features.

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  • November 29, 2017
  • Journal Articles

Quantitative Systems Pharmacology Approach for Risk Assessment on Drug-Induced Proarrhythmic Effects with Physiologically Based Pharmacokinetic Model

Authors: Nakamura M, Yoneyama F, Hirata A, Fujishima K, Saito R
Publication: J Pharmacol Toxicol Methods
Keywords: PBPK modeling, qsp, safety research
Software: GastroPlus®
  • Click to View

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