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May 1, 2018

In vitro/in silico approach in the development of simvastatin-loaded self-microemulsifying drug delivery systems.

Objective

The aims of this study were to formulate simvastatin (SV)-loaded self-microemulsifying drug delivery systems (SMEDDS), and explore the potential of these drug delivery systems to improve SV solubility, and also to identify the optimal place in the gastrointestinal (GI) tract for the release of SV using coupled in vitro/in silico approach.

 

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