Leverage the science, models and refined algorithms GastroPlus users rely on—now with a more intuitive interface, faster processing, time-saving reusable assets, and streamlined workflows for faster and easier PBPK modeling and simulation.
almost here

Functionality
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Others
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GastroPlus
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Includes animal models
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Rat, dog, mouse, monkey
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Rat, dog, mouse, monkey, rabbit, minipig
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Includes multiple human populations
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Includes pediatric and geriatric populations
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Incorporates drug product batch dissolution data into a PBBM model (P-PSD)
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Minimal or full absorption modeling
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Offers cutting-edge virtual replicate BE study designs
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Unlimited victim/perpetrator compounds for polypharmacy DDI simulations
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Offers in-platform data visualization
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Can run and visualize multiple simulations in one run
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Extends capabilities with custom R/Python code for complex reporting, plotting & functionality
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Includes full equation guide
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Offers integrated AI/ML property prediction for ADME endpoints
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Provides real-time model guidance using AI and expert decision trees
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AI-assisted data extraction capabilities from publications, reports, and more
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Automates workflows using REST API
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Allows unlimited forms for formulation design
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Offers integrated noncompartmental PK analysis
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Unlimited metabolite tracking around the body
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Allows pre-simulation set-up check
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Customizable licensing to support company needs
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Accelerate model building by saving projects as templates or using included ready-made templates

Dose multiple compounds to multiple virtual patient populations at once

Improve your understanding through high-level summaries and deep dive views of your predictions

Improved accuracy in the #1-rated absorption model with enhanced capabilities validated in collaboration with the FDA and pharmaceutical companies

Upgraded trial designs and robust statistical engines to support your regulatory interactions

Get real-time model guidance and answers to technical questions with your virtual embedded expert and AI-powered tools

Minimize error and improve efficiency by building, executing & manipulating GPX projects and accessing external computational engines

Open science support provides full transparency to the model structures that drive your predictions

Flexible schedules cover all your study scenarios
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How can I access GPX.2?
Download and installation is now available for all existing GastroPlus clients. If you are a current customer and have questions, reach out to your Simulations Plus account manager. If you are not yet a client but would like to learn more about licensing our software, you can schedule a software demo here.
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My IT department has technical questions about installing GPX.2. How can I get them answers?
We recognize that understanding the cybersecurity and technical requirements of a new software platform is a critical component of IT’s role within an organization. Please have someone from your IT team watch our on-demand webinar.
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What training is available to get my team up to speed?
We have multiple in-person and online workshops available for registration. You can also request an in-person training for your organization by contacting Peter Kilford.
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How do I get the most out of GastroPlus?
To maximize your use of GastroPlus, we highly recommend a few options:
- If you’re relatively new to GastroPlus, review our GPX Tutorial Series. Our experts will explain how to navigate the interface and perform a variety of tasks.
- If you are a more experienced GastroPlus user and want in-depth instruction, consider registering for one of our focused on-demand courses. These can be taken at your convenience.
- Join the GastroPlus User Group and learn from your industry peers.
- Sign up to receive our GastroPlus newsletter, which will provide sneak peeks at upcoming software releases, webinars, and in-person events.
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What is new in GPX.2?
Check out all the new features and enhancements in the Product Brochure.
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My quality management team would like to go through the qualification process. Any shortcuts you can point me to?
Your company’s GPX installation directory contains a validation suite – at no extra cost to you! This is an easy, streamlined option to run a series of automated simulations to ensure your installed version is producing the correct results.