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    • GastroPlus®
      • GastroPlus®
        GastroPlus®
        PBBM/PBPK
        View Product

        PBBM / PBPK modeling & simulation software package which simulates all major dosing routes and drug-drug interactions (DDIs) in virtual human & animal population groups.

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      • Modules

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        • Simulations Plus Releases GastroPlus® Version 9.8.3
        • Download Latest GastroPlus Version
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    • MonolixSuite™
      • MonolixSuite™
        MonolixSuite™
        PK/PD
        View Product

        Easy, fast, and powerful tool for parameter estimation in non-linear mixed effect models, model diagnosis and assessment, and advanced graphical representation.

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      • Suite

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        • Simulx®

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    • ADMET Predictor®
      • ADMET Predictor®
        ADMET Predictor®
        AIDD/ML
        View Product

        Flagship machine learning platform for ADMET modeling with extended capabilities for data analysis, metabolism prediction, high-throughput pharmacokinetic simulation (HTPK), and AI-driven drug design.

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      • Modules

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        • ADMET Modeler™
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        • Download the AP11 Flyer
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        • ADMET Predictor® 11 Release Webinar
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    • DILIsym®
      • DILIsym®
        DILIsym®
        QST
        View Product

        Quantitative Systems Toxicology (QST) software designed to be used during drug development to provide deeper insight into the mechanisms responsible for observed drug-induced liver injury (DILI) responses.

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    • DDDPlus™
      • DDDPlus™
        DDDPlus™
        PBBM/PBPK
        View Product

        A mechanistic simulation engine for the in vitro dissolution experiment that predicts in vitro disintegration and dissolution of pharmaceutical dosage forms.

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        • ADMET Predictor®

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        • Simulations Plus Releases DDDPlus™ Version 6
        • DDDPlus™ 6 Webinar
    • NAFLDsym®
      • NAFLDsym®
        NAFLDsym®
        QSP
        View Product

        Quantitative Systems Pharmacology (QSP) software for mechanistic mathematical modeling of nonalcoholic fatty liver disease (NAFLD.)

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        • Overview

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        • NAFLDsym® Product Brochure
        • QSP/QST Capabilities Flyer
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        • NAFLDsym® Video: Prediction of Clinical Response to Hepatic AMPK Activation
        • NAFLDsym v2A Release Webinar
    • MembranePlus™
      • MembranePlus™
        MembranePlus™
        PBBM/PBPK
        View Product

        A detailed modeling & simulation program for in vitro metabolism & transport studies.

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        • ADMET Predictor®

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        • Simulations Plus Releases MembranePlus™ 3.0
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    • PKanalix®
      • PKanalix®
        PKanalix®
        PK/PD
        View Product

        Graphical and interactive software for non-compartmental and compartmental analysis.

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        • Watch MonolixSuite™ R2023 Webinar
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    • Simulx®
      • Simulx®
        Simulx®
        PK/PD
        View Product

        A powerful and flexible simulator for clinical trial pharmacometrics.

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        • Watch MonolixSuite™ R2023 Webinar
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    • IPFsym®
      • IPFsym®
        IPFsym®
        QSP
        View Product
        IPFsym®

        Quantitative Systems Pharmacology (QSP) software providing the ability to predict the efficacy of drugs being developed to treat idiopathic pulmonary fibrosis (IPF.)

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        • Pulmonary Package

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    • ILDsym®
      • ILDsym®
        ILDsym®
        QSP
        View Product
        ILDsym®

        Quantitative Systems Pharmacology (QSP) software for mechanistic mathematical modeling of interstitial lung disease (ILD) associated with system sclerosis (SSc.)

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    • RENAsym®
      • RENAsym®
        RENAsym®
        QST
        View Product
        RENAsym®

        Quantitative Systems Toxicology (QST) software for predicting and understanding drug-induced kidney injury.

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      • Shortcut

        • RENAsym® Version 1A Press Release
        • RENAsym, a QST Model to Predict Drug-Induced Kidney Injury
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    • MedChem Designer™
      • MedChem Designer™
        MedChem Designer™
        ADMET/ML
        View Product
        MedChem Designer™

        FREE chemical sketching software tool which combines innovative molecule drawing features.

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        • Download for Free
        • Free 30-Day Evaluation of ADMET Predictor®

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        QSP Software

        QSP software for predicting efficacy & guiding design.

        Contact Us

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Shawn O'Connor

Shawn O’Connor

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Will Frederick

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Cognigen
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Simulations Plus
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Quantitative Systems Pharmacology
Amparo de la Peña

Amparo de la Peña

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Cognigen
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Andrew Rokitka

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Quantitative Systems Pharmacology
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Kathleen Morgan-Kehr

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Assoc. Dir., Sr. Prin. Sci.
Quantitative Systems Pharmacology
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Executive Director, HR
Simulations Plus, Inc.
Neil Miller

Neil Miller

VP, Simulation Sciences
Simulations Plus
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Peter Kilford

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