Simulations Plus

First Release of New Product in 10 Years; Provides Unique In Vitro Permeability Capabilities and Creates Cross-Selling Opportunities

$200,000 Grant to Support Enhancements to Company’s Industry-Leading GastroPlus Software

Interim release adds several user-requested functions

Upgrade extends technological lead, adds several user-requested functions

Cash dividend declared of $0.05 per share

Investor Conference Call Scheduled for Friday, July 25, at 1:15 PM PDT

A leading provider of clinical trial data analysis to expand company’s offerings

Revenues up 20.9%, Net Income up 31.6%

Conference Call to be on Tuesday, July 8, at 4:15 PM ET

New All-time Record Revenues in Third Quarter

Major upgrade improves all predictions, adds new ones

Upgrades include powerful new optical structure recognition feature

Company Buys Out Perpetual Royalty Agreement

Cash dividend declared of $0.05 per share

Company completes 26th consecutive profitable quarter

Conference Call to be on Wednesday, April 9, at 4:15 PM ET

Research Institute for Liver Diseases to Offer Company’s Consulting Services