Webinars

Featured Webinars:

ADMET Predictor 8.1: Efficiently handle LARGE data sets

Incorporating transporter kinetics into PBPK models

 

Watch Past Webinars

ADMET Predictor 8.1: Efficiently handle LARGE data sets

Building off of the successful launch of the redesigned ADMET Predictor 8.0, many substantial enhancements have been made throughout version 8.1 to improve performance. The most significant is that ADMET Predictor 8.1 is now available as both 32- and 64-bit executables. Additionally, interface functions and model-building processes have been optimized to more effectively handle large data sets.

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Incorporating transporter kinetics into PBPK models

12.1.16 - One of the previous webinars in this series discussed transporters affecting drug absorption. This webinar will focus more on transporters involved in drug distribution and elimination. A brief summary of current information on transporter expression levels will be followed by a description of options for including transporters in the GastroPlus™ PBPK model. gastroplus

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GastroPlus™ PBPK modeling as a tool to ensure target performance of a generic drug product

10.6.16 - For a generic drug, the objective is to develop a formulation/process that would result in the product performance equivalent to that of the reference (innovative) product throughout the product life-cycle. gastroplus

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PKPlus™ – The next-generation software for preclinical and clinical trial data analysis

9.13.16 - Every lead compound that enters preclinical testing warrants some form of noncompartmental analysis (NCA), with promising candidates that are heading into clinical trials requiring validated NCA as part of new drug applications submitted to regulatory agencies. pkplus

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Using GastroPlus™ Modeling to Eliminate Bridging Clinical Studies for Late

6.9.16 - This webinar will focus on 2 case studies from scientists from Roche and Janssen describing the use of GastroPlus PBPK modeling to eliminate bridging clinical studies.

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ADMET Predictor – Your user experience redefined…

4.20.16 - The user interface in ADMET Predictor was completely rewritten for version 8. In this webinar, we demonstrate the new tools available in ADMET Predictor 8 using examples from various data sets, e.g., BACE1 inhibitors.

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in-vitro-dissolution

Reimagine the In Vitro Dissolution Experiment with DDDPlus™ 5.0…

3.31.16 - In this webinar, we present the many improvements made in the new DDDPlus 5.0. gastroplus

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Unified dissolution / precipitation model and its use predicting absorption

3.3.16 - This webinar will focus on the description of a novel mechanistic mathematical model developed to describe in vitro dissolution and precipitation data and how the model can be used in a wider PBPK framework to explain complex absorption profiles for weak bases. gastroplus dddplus

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Application of Cellular Permeability Simulation and PBPK Models to Capture

12.10.15 - In this GastroPlus™ User Group webinar, we will discuss the validation of passive permeability estimates in MembranePlus™ based on molecular structure alone for a library of diverse compounds and how it compares to Kubinyi's drug partitioning theory. membraneplus gastroplus

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Applications of customized GastroPlus™ models

10.15.15. - This GastroPlus™ User Group video explores how the ACAT model, with customized refinement of the model parameters or design of the model structure, can provide valuable insights to address various aspects of challenges in biopharmaceutics, including PBPK modeling-based in vitro-in vivo correlations. gastroplus

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