Webinars

Featured Webinars:

MembranePlus™ v2 webinar: Stimulate your kinetic understanding…

ADMET Predictor 8.1: Efficiently handle LARGE data sets

Watch Past Webinars

Understanding dermal drug disposition using TCAT™ – a novel PBPK model

9.14.17 - Scientists from GlaxoSmithKline and Simulations Plus have collaborated to develop a mathematical model, Transdermal Compartmental Absorption & Transit (TCAT™), that allows better understanding of drug penetration through the skin while accounting for the formulation characteristics, evaporation and precipitation effects that influence dermal delivery.

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MembranePlus™ v2 webinar: Stimulate your kinetic understanding…

9.7.17 - We are pleased to announce the release of MembranePlus™ v2! This version takes modeling of in vitro systems to the next level, allowing you to capture all relevant information from your experiments.

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Use of oral absorption modelling to characterize drug release and absorption of a BCS II compound from IR formulations

3.28.17 - The presentation illustrates the applicability and impact of mechanistic absorption modelling to support oral formulation development and improve the prediction of drug bioavailability from immediate-release formulations.

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GastroPlus™ 9.5 Release Webinar: Something for Everyone

3.7.17 - We are pleased to announce the release of GastroPlus™ 9.5! This version has something for all users of our top-ranked PBPK modeling platform.

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ADMET Predictor 8.1: Efficiently handle LARGE data sets

1.31.17 - Building off of the successful launch of the redesigned ADMET Predictor 8.0, many substantial enhancements have been made throughout version 8.1 to improve performance. The most significant is that ADMET Predictor 8.1 is now available as both 32- and 64-bit executables. Additionally, interface functions and model-building processes have been optimized to more effectively handle large data sets.

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Incorporating transporter kinetics into PBPK models

12.1.16 - One of the previous webinars in this series discussed transporters affecting drug absorption. This webinar will focus more on transporters involved in drug distribution and elimination. A brief summary of current information on transporter expression levels will be followed by a description of options for including transporters in the GastroPlus™ PBPK model. gastroplus

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GastroPlus™ PBPK modeling as a tool to ensure target performance of a generic drug product

10.6.16 - For a generic drug, the objective is to develop a formulation/process that would result in the product performance equivalent to that of the reference (innovative) product throughout the product life-cycle. gastroplus

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PKPlus™ – The next-generation software for preclinical and clinical trial data analysis

9.13.16 - Every lead compound that enters preclinical testing warrants some form of noncompartmental analysis (NCA), with promising candidates that are heading into clinical trials requiring validated NCA as part of new drug applications submitted to regulatory agencies. pkplus

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Using GastroPlus™ Modeling to Eliminate Bridging Clinical Studies for Late

6.9.16 - This webinar will focus on 2 case studies from scientists from Roche and Janssen describing the use of GastroPlus PBPK modeling to eliminate bridging clinical studies.

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ADMET Predictor – Your user experience redefined…

4.20.16 - The user interface in ADMET Predictor was completely rewritten for version 8. In this webinar, we demonstrate the new tools available in ADMET Predictor 8 using examples from various data sets, e.g., BACE1 inhibitors.

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