Master the client-side integration of ADMET Predictor® via its REST API. This tutorial provides a “whirlwind tour” of API endpoints (URIs), starting with basic ADMET property predictions using SMILES strings. It covers complex workflows such as generating pKa microstate displays and atomic property images directly from the server. Learn how to perform high-throughput pharmacokinetic (HTPK) simulations for fraction absorbed ($F_{a}$) and bioavailability ($F_{b}$), as well as how to execute dose optimization studies. The video also explains the run command endpoint, which replicates the full power of the ADMET Predictor command-line interface, allowing for advanced tasks like metabolite generation and compound standardization through the API.