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December 2023 GastroPlus Newsletter
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December 2023 GastroPlus Newsletter
  • December 20, 2023
  • Blog

December 2023 GastroPlus Newsletter

Authors: Padron A
Keywords: ddI, gastroplus, gi tract, Long Acting Injectable, ocular, pbbm, PBPK
Software: GastroPlus®

GastroPlus® Newsletter December 2023

  • Read More
Creating Quality by Committing to Compliance in Clinical Research
  • December 13, 2023
  • Blog

Creating Quality by Committing to Compliance in Clinical Research

Authors: Newman R
Keywords: clinical research, compliance, simulation-based approaches
Division: Clinical Simulations & Medical Communications

In the highly regulated world of clinical research, compliance is an ongoing concern, but can be viewed as an annoying and costly item to check off a regulatory to-do list.

  • Read More
  • Click to View
December 2023 News/Events
  • December 5, 2023
  • Blog

December 2023 News/Events

Keywords: CHI, drug discovery, fih, pbbm, PHUSE US Connect, SOT

Fully Power Your First-in-Human Predictions

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How to Select Your First-in-Human Modeling and Simulation Software Platform
  • November 27, 2023
  • Blog

How to Select Your First-in-Human Modeling and Simulation Software Platform

Authors: Kilford P
Keywords: clinical trial, fih, FIH/Phase I, first-in-human, population analysis
Division: PBPK

Determining appropriate dosage for your first in human (FIH) clinical trials is critical.

  • Read More
November 2023 GastroPlus Newsletter
  • November 16, 2023
  • Blog

November 2023 GastroPlus Newsletter

Authors: O’Connor D
Keywords: ACAT model, biologics, gastroplus, metabolism
Software: GastroPlus®
Division: PBPK

GastroPlus® Newsletter November 2023

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November 2023 News/Events
  • November 6, 2023
  • Blog

November 2023 News/Events

Keywords: ACOP, ai drug discovery, DMPK, GastroPlus Workshop, pbbm, PBPK, qsp, QST modeling
Division: PBPK

Are your clinical trials showing potential liver toxicity?

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The Keys to Making Good Models from Chemical Structures
  • November 3, 2023
  • Blog

The Keys to Making Good Models from Chemical Structures

Authors: Jones J
Keywords: admet predictor, ANNE models, Chemical structure, CYP, modeling and simulation
Software: ADMET Predictor®
Division: Cheminformatics

There are many different things that make a model "good."

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October 2023 News/Events
  • October 12, 2023
  • Blog

October 2023 News/Events

Keywords: AAPS PharmSci 360, ADMET, ai drug discovery, ionization, Nonlinear Mixed Effect (NLME) modeling
Division: Clinical Pharmacology and Pharmacometrics (CPP), PBPK, Quantitative Systems Pharmacology (QSP)

Using ionization modeling to inform drug discovery and decision-making

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October 2023 GastroPlus Newsletter
  • October 11, 2023
  • Blog

October 2023 GastroPlus Newsletter

Authors: O’Connor D
Keywords: AAPS PharmSci 360, drug absorption, drug products, ionization, PBPK modeling
Software: GastroPlus®
Division: PBPK

GastroPlus® Newsletter October 2023

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The Difficulty with Data: Considerations for Training Your AI/ML Algorithms for Drug Discovery
  • September 22, 2023
  • Blog

The Difficulty with Data: Considerations for Training Your AI/ML Algorithms for Drug Discovery

Authors: Jones J
Keywords: absorption distribution metabolism and excretion (ADME), AI-Driven Drug Design, computer aided drug design (CADD), early drug discovery, in silico prediction, machine learning (ML), pharmacokinetic (PK) properties
Software: ADMET Predictor®, GastroPlus®
Division: Cheminformatics

Effective de novo drug design is a long-standing but elusive goal for computational chemistry.

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September 2023 GastroPlus Newsletter
  • September 12, 2023
  • Blog

September 2023 GastroPlus Newsletter

Authors: O’Connor D
Keywords: AAPS PharmSci 360, gastroplus, GastroPlus Workshop, International Society for the Study of Xenobiotics (ISSX), pharmaceutical
Software: GastroPlus®
Division: PBPK

GastroPlus® Newsletter September 2023

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September 2023 News/Events
  • September 6, 2023
  • Blog

September 2023 News/Events

Keywords: clinical trial, GastroPlus Workshop, International Society for the Study of Xenobiotics (ISSX), qsp
Division: PBPK

Increasing the probability of success in clinical trials

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August 2023 GastroPlus Newsletter
  • August 8, 2023
  • Blog

August 2023 GastroPlus Newsletter

Authors: O’Connor D
Keywords: GastroPlus Workshop, International Society for the Study of Xenobiotics (ISSX), pbbm, regulatory affairs, U.S. Food and Drug Administration (FDA)
Software: GastroPlus®
Division: PBPK

GastroPlus® Newsletter August 2023

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August 2023 News/Events
  • August 1, 2023
  • Blog

August 2023 News/Events

Keywords: ai drug discovery, drug development, GastroPlus Workshop, PBPK modeling, pulmonary delivery, QSP model
Software: DILIsym®, GastroPlus®
Division: Clinical Pharmacology and Pharmacometrics (CPP), PBPK, Quantitative Systems Pharmacology (QSP)

Quickening the pace of drug discovery with AI

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July 2023 GastroPlus Newsletter
  • July 11, 2023
  • Blog

July 2023 GastroPlus Newsletter

Keywords: CRS, gastroplus, intraocular injections, model based drug development
Software: GastroPlus®
Division: PBPK

GastroPlus® Newsletter July 2023

  • Read More
July 2023 News/Events
  • July 5, 2023
  • Blog

July 2023 News/Events

Keywords: admet predictor, drug development, Immunetrics, Oncology Drug Development, pbbm
Software: ADMET Predictor®, DILIsym®, GastroPlus®
Division: Clinical Pharmacology and Pharmacometrics (CPP), PBPK, Quantitative Systems Pharmacology (QSP)

Expanding our Immunology and Oncology Drug Development Capabilities

  • Read More
June 2023 GastroPlus Newsletter
  • June 13, 2023
  • Blog

June 2023 GastroPlus Newsletter

Keywords: admet predictor, CRS Annual Meeting Expo, drug design, PBPK modeling
Software: GastroPlus®
Division: PBPK

Workshops and Webinars

  • Read More
June 2023 News/Events
  • June 6, 2023
  • Blog

June 2023 News/Events

Keywords: consult & coach, CRS, EAVPT, PAGE, pulmonary, SMB, workshops
Software: ADMET Predictor®, GastroPlus®, ILDsym™, IPFsym®
Division: Clinical Pharmacology and Pharmacometrics (CPP), PBPK, Quantitative Systems Pharmacology (QSP)

Explore modeling and simulation summer school opportunities inside

  • Read More
May 2023 GastroPlus Newsletter
  • May 9, 2023
  • Blog

May 2023 GastroPlus Newsletter

Keywords: gastroplus, gastroplus user group, PBPK modeling, workshops
Software: GastroPlus®
Division: PBPK

Happy Spring… even though this year I have experienced the most severe case of “hay fever” ever.

  • Read More
May 2023 News/Events
  • May 2, 2023
  • Blog

May 2023 News/Events

Keywords: AI-Driven Drug Design, ASCO Annual Meeting, CSPS 2023, GastroPlus Workshop, Ninth Joint Sheffield Conference on Chemoinformatics, PAGE 2023, pulmonary absorption
Software: ADMET Predictor®, GastroPlus®, ILDsym™, IPFsym®
Division: Clinical Pharmacology and Pharmacometrics (CPP), PBPK, Quantitative Systems Pharmacology (QSP)

Early Drug Discovery Application, FIH Predictions Workshops, and new software & consulting bundles

  • Read More
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