Simulations Plus

Large Pharmaceutical Company Renews Multi-year License

Important New Improvements Added to the Company's Gold Standard Software

Company Sets New Record for Second Quarter Revenues and Earnings

Conference Call to be on Thursday, April 13, at 4:15 PM EDT

Dramatic Improvements in Speed and Function Expected to Improve Drug Discovery

Large Customer Renews Annual Global License for GastoPlus ™

Call To Be Held On Tuesday, December 13, at 4:30 PM EST

Completion of Two-Year Development Program Adds Major New Functionalities

Company Plans Conference Call Shortly After Release

Function to be Moved In-House for Greater Operating Efficiency

hERG Potassium Channel Blocking Affinity Models Important Cardiac Toxicity

Product Manager to Become Full-time Field Representative

New Product Line and Key Employee Expand Software Offerings and Science Staff

Termination by Mutual Agreement to Result in Reduced Expenses

Name change, new features, compatibility with ADMET Predictor™

New core product is first in industry