Contract Signals Long-Term Demand for Simulations Plus' Software and Consulting Services

ANTI-HIV Predictive Models Released by Simulations Plus
Extensions to ADMET Predictor(™) Software Enhance Anti-HIV Activity Discovery Capabilities

Simulations Plus Reports First Quarter FY2007 Financial Results
Record First Quarter Sees Pharmaceutical Revenues Jump 314%

Simulations Plus Announces First Quarter Fiscal Year 2007 Earnings Conference Call
Conference Call to be on Tuesday, January 16, at 4:15 PM EST

Simulations Plus Flagship Software To Aid Government Research Projects
U.S. FDA Licenses GastroPlus(™)

Simulations Plus Receives Another Large Pharmaceutical Software License Renewal
Large Pharmaceutical Company Renews Global Software Licenses

Simulations Plus Receives Large Multi-Year Pharmaceutical Software License
Hoffmann-LaRoche Renews Multi-year Software Licenses

Simulations Plus Releases GastroPlus(™) 5.2
Flagship Software Product Improvements Provide Greater Accuracy and Convenience

Simulations Plus Releases ClassPharmer(™) 4.2
Improvements Provide New Capabilities Requested by User Community

Simulations Plus Reports Preliminary FY2006 Financial Results
Annual Revenues Up 23%, Net Earnings Up 158%

Simulations Plus Announces Fiscal Year 2006 Earnings Conference Call
Conference Call to be on Thursday, November 9, at 4:15 PM EST

Japan’s NIHS Licenses Simulations Plus ClassPharmer Software for Five Years
National Institute of Health Sciences is Equivalent to U.S. F.D.A.

Simulations Plus Releases ADMET Predictor(™) 2.0
Powerful Predictive Software Enhanced With Superior Molecular Modeling Capabilities

Simulations Plus Announces Large Consulting Contract
Company Underscores Guidance at Fiscal Year End

Simulations Plus Stock Splits 2-for-1
CEO to be Interviewed by the Wall Street Reporter

Simulations Plus Announces Stock Dividend
Board of Directors Approves Two-for-One Stock Split

Simulations Plus Reports Third Quarter FY2006 Financial Results
Company Sets New Record for Third Quarter Revenues and Earnings