Presented by Lara Clemens at SLP MIDD+ Virtual Conference February 16th-17th, 2022
Discovery Track Poster Presentation: Modeling tautomer preference
Presented by Marvin Waldman at SLP MIDD+ Virtual Conference February 16th-17th, 2022
Pre-Clinical Track Poster Presentation: QST Modeling of Drug Induced Acute Proximal Tubule Epithelial Cell Injury and Associated Renal Hemodynamic Responses
Presented by Nader Hamzavi at SLP MIDD+ Virtual Conference February 16th-17th, 2022
Discovery Track: How we leverage automation for data mining, preprocessing & curation
Presented by Phyo Phyo Kyaw Zin at SLP MIDD+ Virtual Conference February 16th-17th, 2022
Pre-Clinical Track: Ophthalmic clinical pharmacokinetic/pharmacodynamic prediction using PBPK model validated against preclinical datasets
Presented by Maxime LeMerdy at SLP MIDD+ Virtual Conference February 16th-17th, 2022
Discovery Track: AIDD with external models
Presented by Michael Lawless at SLP MIDD+ Virtual Conference February 16th-17th, 2022
Pre-Clinical Track: Translational Modeling of Relapsing Mouse Models to Inform Regimen Selection in Tuberculosis
Presented by James Clary at SLP MIDD+ Virtual Conference February 16th-17th, 2022
Discovery Track: Modeling CYP sites of metabolism in ADMET™ Predictor
Presented by Pankaj R. Daga at SLP MIDD+ Virtual Conference February 16th-17th, 2022
Simulations Plus University+ Program
The University+ program offers one-year access to Simulations Plus software to students and educators at accredited universities worldwide. Learn more from Divisional President, John DiBella.
Discovery Track: HTPK simulations using the new REST API + platform update
Presented at SLP MIDD+ Virtual Conference February 16th-17th, 2022
Welcome to the 2022 MIDD+ Scientific Conference and Keynote Speaker
Welcome and Introductions hosted by Arlene Padron.
Capturing Interpatient Variability with SimPops
SimPops provide significant value for drug development. "The SimPops are the Crown Jewel".
In Vivo Extrapolation of Precipitation with Complex Dissolution Experiments
DDDPlus provides complex models to handle: membrane dissolution, biphasic dissolution and artificial stomach duodenum test.
Applicability of Existing Prediction Methods to Non-Oral Routes of Delivery
Discuss advances made with PBPK modeling for both oral and non-oral routes for the first in human predictions
MIDD in Preclinical Drug Development
Providing a case for why you should focus on preclinical verification when using Physiologically Based Pharmacokinetic (PBPK) modeling for First-In-Human (F.I.H) pharmacokinetic predictions.
RENAsym, a QST Model to Predict Drug-Induced Kidney Injury
Drug-induced kidney injury or acute kidney injury (AKI) is one of the major reasons for drug failure behind cardiovascular and liver injuries
Mathematical Modeling in Industry: Building Models to Advance Drug Development
QSP models are designed to characterize biological systems, representing details such as disease pathophysiology, drug pharmacology, and pathways of toxicity
Pulmonary PBPK Modeling for Inhaled Products: Antibiotic Case Studies
What are we doing for inhaled products today?
Quantitative Systems Toxicology Modeling Using DILIsym Suggests That Drug-Induced Liver Injury (DILI) Can Be Enhanced by Co-administered Drugs and Mitigated by Mitochondrial Biogenesis
Drug-induced liver injury (DILI) can be enhanced by polypharmacy if co-administered drugs induce toxicity via mechanisms that have overlapping pathways.