• Blog

November 2021 News/Events

Keywords: AIDD Module, gastroplus, monolixsuite, University+
Division: Cognigen, DILIsym Services, Lixoft, Simulations Plus

The software development team remains committed to improving our state-of-the-art software tools, educating scientists worldwide with the best and most innovative science, and advancing in silico modeling and simulation.

Check out the key features in the latest version of GastroPlus!

California

Simulations Plus

 

ADMET Predictor® is the flagship machine learning platform for ADMET modeling. Binge the latest software tutorials on YouTube!

Working with Files

Working with Data & Graphs

Using the AIDD module

Learn More

New York

Cognigen

 

Resident ClinPharm Services

Are you having trouble hiring an experienced pharmacometrician/clinical pharmacologist to support your development programs? Do you need advice from someone who has experience with multiple successful regulatory submissions and who can offer suggestions to prevent future challenges?

We’ve been serving pharma & biotech companies big and small for almost 30 years. We offer a variety of collaboration options to suit your company’s needs

Solving the global COVID-19 pandemic requires innovative and integrative new approaches to accelerate drug development. Visit the ACoP virtual poster hall to see how we’re supporting large pharmaceutical companies.

-Population pharmacokinetics analysis for molnupiravir in Adults With COVID-19

Contact the Experts

France

Lixoft

 

Built for Model Informed Drug Development (MIDD) computing! In the latest version of MonolixSuite®, we provide you with a complete modeling & simulation workflow.

Stream what’s new in MonolixSuite R2021 webinar

Science in action! Visit the virtual poster hall at the ACoP Conference, Nov. 8-12.

Validation of non-compartmental analysis (NCA) and bioequivalence results of PKanalix over more than 180 datasets covering several thousand PK profiles

A library of parent-metabolite models for the MonolixSuite

Optimizing the sample size of a bridging study using Simulx, an application of the MonolixSuite

Corporate news

University+ Program

 

The University+ program offers one-year access to Simulations Plus software to students and educators at accredited universities worldwide, renewable if eligibility conditions are met.  Our goal is to increase modeling and simulation (M&S) learning and education that will promote the next generation of scientists and set them up today for success tomorrow.

Enroll Today

North Carolina

DILIsym Services

 

Our multidisciplinary scientists, with backgrounds in mathematics, engineering, pharmacology, biochemistry, and immunology will be presenting at several conferences this month.  Sharing the science on QST and QSP platforms to support the development of safe and effective treatments.

ACoP Nov. 8-12

  • Scott. Q. Siler: Suppressing TGF-b activation to reduce lung fibrosis: In search for an efficacious dose regimen for alpha V integrin inhibitors
  • Zackary R. Kenz: CARDIOsym QSP model prediction of wound healing response following myocardial infarction

Kidney Week Nov. 4-7

  • Nader Hamzavi: Quantitative Systems Toxicology (QST) Modeling of Drug-Induced Acute Proximal Tubule Epithelial Cell Injury and Associated Renal Hemodynamic Responses
  • Nader Hamzavi:: Mechanistic Modeling of Kidney-Injury Molecule 1 (KIM-1) as a Biomarker for Cisplatin-Induced AKI

AASLD Liver Meeting Nov. 12-15
Session: Hepatotoxicity: Pathogenesis & Mechanisms; Drug Metabolism, Toxicity, & Therapeutics; Predictors of Drug Toxicity

  • Jeff Woodhead: Advancing CGRP antagonists using QST modeling to characterize next-in-class compounds compared to the hepatotoxic first in class telcagepant

Session: NAFLD & NASH: Therapeutics – Pharmacologic & Other

  • Chistina Battista: QSP model predicts lack of efficacy for cenicriviroc, a ccr2/5 antagonist, in NAFLD/NASH patients
  • Lisl Shoda: Yo-yo dieting predicted to contribute to fibrosis score reductions in untreated (placebo) cohorts

View Conference Calendar

Career Opportunities

Remote & office positions are available at any of our corporate locations. Apply Today.

  • Application Manager
  • Business Development Director, Quantitative Systems Pharmacology
  • Chief Revenue Officer (CRO)
  • Microsoft Dynamics Analyst and Developer
  • PBBM PBPK Modeling Scientist
  • Pharmacometrician
  • QSP/QST Modeling Scientist
  • R Data Programmer
  • Research Fellow – Regulatory Strategies
  • Senior Director, Pharmacometric Services

Find a New Career

 

You probably know of the many QSP/QST platforms available for licensing and consulting from the DILIsym Services division of Simulations Plus, but did you know that all of those great platforms started with a collaboration between us and our customers?

 

Learn More – Custom QSP

 

 

 

 

Vision Mission & Values

Read about our commitments, core values, and guiding principles for a better tomorrow. View our VMV statement.

Copyright © 2021 Simulations Plus, All rights reserved.

Simulations Plus, Inc. Corporate Headquarters
42505 10th Street West
Lancaster, CA 93534
Telephone: +1-661-723-7723

Cognigen Corporation, a Simulations Plus company
1780 Wehrle Drive, Suite 110
Buffalo, NY 14221-7000
Telephone: +1-716-633-3463

DILIsym Services, a Simulations Plus company
Six Davis Drive
PO Box 12317
Research Triangle Park, NC 27709
Telephone: +1-919-558-1323

Lixoft, a Simulations Plus company
8 rue de la Renaissance Batiment D
92160 Antony, France
Telephone: +33 9 72 53 91 80