ADMET Predictor® Tutorial Series: HTPK Part 1

Authors: Jamois E
Software: ADMET Predictor®
Division: Cheminformatics

This tutorial for ADMET Predictor provides a deep dive into the HTPK (High-Throughput Pharmacokinetics) module. It covers the setup of oral and IV simulations using rat or human physiologies, running multi-dose comparisons (e.g., 1mg vs. 100mg) to identify concentration-dependent absorption, and interpreting complex PK output data including AUC, halflife, and volume of distribution. The video also features advanced data visualization techniques, such as identifying solubility-limited and permeability-limited compounds through 2D and 3D property projections, aligning with the BCS (Biopharmaceutics Classification System).