Enable ADMET Predictor® functionality within commercial platforms like Spotfire, Live Design, or custom Python scripts using the REST API. This tutorial focuses on the server-side setup, guiding you through the installation of the admet_predictor_service.exe binary. Key configuration steps include setting up a writable support folder for QSAR model files, configuring the Flexera license server communication, and choosing between upfront license checkout or shared license modes. The video also covers the use of encryption with SSL certificates and how to troubleshoot the installation using the service log files to ensure successful initialization.