Jessica Spires, Ph.D.
Dr. Jessica Spires is a Principal Scientist at Simulations Plus, Inc. Since 2013, she has focused on PBPK modeling of non-oral routes of administration, including dermal, ocular, and pulmonary administration, in the GastroPlus™ and MembranePlus™ software platforms. She is currently the principal investigator on two FDA grants, focusing on transdermal drug products quality and performance attributes via enhanced virtual bioequivalence simulations, and on PBPK/PD modeling of ophthalmic drug products to support translation from pre-clinical species to human. She is a graduate of Case Western Reserve University with a PhD in biomedical engineering.