Over the past several years, the Simulations Plus team has been revolutionizing oral small molecule PBPK/PBBM modeling with one of the most significant changes in the GastroPlus platform to date.

MembranePlus™ Version 3.0 Release Notes
Our Simulations Plus development team continues to work hard to make MembranePlus the most advanced and reliable simulation of drug absorption and metabolism in cell-based assays in the world today.

Installing ADMET Predictor on Linux OS
Installation instructions for ADMET Predictor® using Linux OS

GastroPlus® v9.7 Patch
Thank you for your interest in GastroPlus.

GastroPlus® v9.7 Patch Installation
We provide patches in between major releases to address issues reported in the current version.

Standalone Installation Instructions for GastroPlus v9.7
Before you begin in order to install GastroPlus, you must have Administrative privileges.

Network Installation Instructions for GastroPlus v9.7
Before you begin: In order to install GastroPlus, you must have Administrative privileges.

Technical Support Hotline
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ADMET Predictor 9.5 Installation
This video shows how to install ADMET Predictor® 9.5

ADMET Predictor 9.5 Release Notes
This new release of ADMET Predictor includes significant enhancements throughout the program, including to the ADMET Modeler™ and MedChem Designer™ modules.

ADMET Predictor 9 Release Notes
This new release of ADMET Predictor includes significant enhancements to the recently introduced HTPK Simulation Module, as well as to the MedChem Studio™ module and ADMET Modeler™