Overview
Hexa Logo of GastroPlus X
GastroPlus®
Important Notice:

Simulations Plus is aware of the issues with Log4J and the licensing module, Flexera. That is one of the reasons why Simulations plus has recently updated our licensing system to Reprise. Reprise has improved security and functionality. We recommend moving into the newer version of our application – GastroPlus version 10.2 – GPX.

  • System Requirements

    Our software is designed to run on Windows 11 (64-bit), Windows 10 (64-bit) or Windows Server 2022 (64-bit). A minimum of 16 GB of RAM is recommended for optimal performance. Our software requires at least 1GB of available hard-drive space for installation.

    Our software runs on Mac operating systems with Windows virtualization.

  • Installation Instructions
  • Licensing

    Reprise Licensing 

    Reprise is the licensing system used for GastroPlus X.2. It will also soon be available for GastroPlus 9.9. Previous versions of GastroPlus will continue using Flexera licensing until they are no longer supported. 

    Licenses can be managed through RLMCloud for real-time, cloud-based licensing (no extra server setup, easy updates, and feature management) or through ActivationPro for on-demand license fulfillment. Both options support standalone or floating licenses for maximum flexibility.  

    We recommend RLMCloud for its simplicity and flexibility—licenses can be activated instantly, updated in real time, and accessed from anywhere without the need to maintain a server. 

    Access is limited to scientists located within fifty (50) miles of the city where the software is installed. 

     

    Flexera Licensing 

    Flexera is the licensing system used for GastroPlus 9.8 and prior. With this system, each user license can be installed on a standalone machine (‘standalone’) or uploaded to a network server (‘floating seat’). It is left to your organization as to how the license(s) will be made available to the user community. 

    The majority of our clients install the software to a network license server (or similar shared resource), as the sharing of licenses between users and across departments provides significant value for companies of all sizes. The restriction is that the user license is only to be accessed by those scientists based within a specific geographical location (within fifty (50) miles of the territorial boundaries of the city where the software is installed). 

    Having trouble? Contact us here for personal assistance.

  • Cloud Service Offerings

    This software platform can be deployed via a cloud-based modeling using Amazon Web Services (EC2), a scalable, reliable, and secure global computing infrastructure, that is the virtual backbone of Amazon.com’s multi-billion dollar online business that has been honed for over a decade.

    You pay only for the software licenses, plus compute power, storage, and other resources you use, with no long-term contracts or up-front commitments.

    Using our cloud model, our customers don’t have to worry about installation deployment, upgrades, licensing, or administration of computing resources, as our dedicated cloud specialists take care of all information technology related tasks, so that our customers can focus on science.

  • Quick Links
ADMET Predictor 12 logo
ADMET Predictor®
Important Notice:

Simulations Plus is aware of the issues with Log4J and the licensing module, Flexera. That is one of the reasons why Simulations plus has recently updated our licensing system to Reprise. Reprise has improved security and functionality. We recommend moving into the newer version of our application – ADMET Predictor version 13.

  • System Requirement

    Our software is designed to run on Windows 11 (64-bit), Windows 10 (64-bit) or Windows Server 2022 (64-bit). A minimum of 16 GB of RAM is recommended for optimal performance. Our software requires at least 1GB of available hard-drive space for installation.

    Our software runs on Mac operating systems with Windows virtualization.

  • Installation Instructions
  • Licensing

    Reprise Licensing 

    Reprise is the licensing system used for ADMET Predictor 13. It will also soon be available for ADMET Predictor. Previous versions of ADMET Predictor will continue using Flexera licensing until they are no longer supported. 

    Licenses can be managed through RLMCloud for real-time, cloud-based licensing (no extra server setup, easy updates, and feature management) or through ActivationPro for on-demand license fulfillment. Both options support standalone or floating licenses for maximum flexibility.  

    We recommend RLMCloud for its simplicity and flexibility—licenses can be activated instantly, updated in real time, and accessed from anywhere without the need to maintain a server. 

    Access is limited to scientists located within fifty (50) miles of the city where the software is installed. 

     

    Flexera Licensing 

    Flexera is the licensing system used for ADMET Predictor 11 and prior. With this system, each user license can be installed on a standalone machine (‘standalone’) or uploaded to a network server (‘floating seat’). It is left to your organization as to how the license(s) will be made available to the user community. 

    The majority of our clients install the software to a network license server (or similar shared resource), as the sharing of licenses between users and across departments provides significant value for companies of all sizes. The restriction is that the user license is only to be accessed by those scientists based within a specific geographical location (within fifty (50) miles of the territorial boundaries of the city where the software is installed). 

  • Cloud Service Offerings

    This software platform can be deployed via a cloud-based modeling using Amazon Web Services (EC2), a scalable, reliable, and secure global computing infrastructure, that is the virtual backbone of Amazon.com’s multi-billion dollar online business that has been honed for over a decade.

    You pay only for the software licenses, plus compute power, storage, and other resources you use, with no long-term contracts or up-front commitments.

    Using our cloud model, our customers don’t have to worry about installation deployment, upgrades, licensing, or administration of computing resources, as our dedicated cloud specialists take care of all information technology related tasks, so that our customers can focus on science.

  • Quick Links
The MonolixSuite logo, a teal hexagon, symbolizes cutting-edge pharmacometrics innovation.A green hexagonal logo for Simulations Plus featuring a white arrow and circle, symbolizing movement.The orange hexagonal logo with a white arrow embodies Simulations Plus' dynamic software solutions.
MonolixSuite™
  • System Requirement

    Our software is designed to run on Windows, Linux, and MacOS X 10.6 or higher. Learn more about system requirements for each operating system here.

  • Installation Instructions
  • Licensing

    Our software is available with independent licenses for PKanalix, Monolix, and Simulx (and their relative applications) if you just need a particular product, or with a bundled license for the complete MonolixSuite. Academic and non-profit organisations can benefit from a free license for non-commercial activities. See License agreement for the Lixoft license agreement for academic and commercial activities.

    MonolixSuite2024R1 licenses can be of the following types:

    • Individual license – named user. The named user can install and run MonolixSuite on a computer.
    • Server license – concurrent access. MonolixSuite run on an application server and a predetermined number of users can use it at the same time.
    • Floating license – concurrent access. The license is hosted by a license server, and MonolixSuite can either run on a server or individual workstations.

    License MonolixSuite™

    Having trouble? Contact us here for personal assistance.