Simulations Plus

Center for Food Safety and Applied Nutrition (CFSAN) to Provide Data

Pharmaceutical Software and Services Revenues Up 18%, Words+ Subsidiary Up 8.3%, Consolidated Earnings Up 32%, and EPS Up 34% from 1QFY10

Conference Call to be on Friday, January 14, at 11:00 AM EST

Record First Quarter and Sustained Multi-year Growth Trend

Fiscal Year Earnings Jump 52.7% on 17.2% Revenue Increase

Conference Call to be on Tuesday, November 30, at 4:15 PM EST

Leading Provider of Simulation and Modeling Software for Pharmaceutical Discovery and Development Scheduled to Present on September 13, 2010; Rodman & Renshaw Annual Global Investment Conference NYC

New Record Fiscal Year Follows Record 1st, 2nd and 3rd Quarters; Rodman & Renshaw Annual Global Investment Conference NYC

Another Record Quarter with Revenues up 15% and Earnings up 30% over Last Year’s Q3

New Record Quarter of $3.1 Million Due to Sustained Growth in Revenues

New System Enables Users to Operate Computer Simply by Looking at It

Sustained Growth in Record Second Quarter and Record First Six Months

Conference Call to be on Thursday, April 15, at 12:00 noon EDT