Record First Quarter Sees Pharmaceutical Revenues Jump 314%

Simulations Plus Announces First Quarter Fiscal Year 2007 Earnings Conference Call
Conference Call to be on Tuesday, January 16, at 4:15 PM EST

Simulations Plus Flagship Software To Aid Government Research Projects
U.S. FDA Licenses GastroPlus(™)

Simulations Plus Receives Another Large Pharmaceutical Software License Renewal
Large Pharmaceutical Company Renews Global Software Licenses

Simulations Plus Receives Large Multi-Year Pharmaceutical Software License
Hoffmann-LaRoche Renews Multi-year Software Licenses

Simulations Plus Releases GastroPlus(™) 5.2
Flagship Software Product Improvements Provide Greater Accuracy and Convenience

Simulations Plus Releases ClassPharmer(™) 4.2
Improvements Provide New Capabilities Requested by User Community

Simulations Plus Reports Preliminary FY2006 Financial Results
Annual Revenues Up 23%, Net Earnings Up 158%

Simulations Plus Announces Fiscal Year 2006 Earnings Conference Call
Conference Call to be on Thursday, November 9, at 4:15 PM EST

Japan’s NIHS Licenses Simulations Plus ClassPharmer Software for Five Years
National Institute of Health Sciences is Equivalent to U.S. F.D.A.

Simulations Plus Releases ADMET Predictor(™) 2.0
Powerful Predictive Software Enhanced With Superior Molecular Modeling Capabilities

Simulations Plus Announces Large Consulting Contract
Company Underscores Guidance at Fiscal Year End

Simulations Plus Stock Splits 2-for-1
CEO to be Interviewed by the Wall Street Reporter

Simulations Plus Announces Stock Dividend
Board of Directors Approves Two-for-One Stock Split

Simulations Plus Reports Third Quarter FY2006 Financial Results
Company Sets New Record for Third Quarter Revenues and Earnings

Simulations Plus Reports Preliminary Results for Third Fiscal Quarter
Company CEO to Present at Wall Street Reporter Small-Cap Discovery Conference

Simulations Plus Releases Combined ADMET Predictor and ADMET Modeler Upgrades
Company's Structure-Property Prediction and Model-Building Software Programs Will Be Sold as a Complete Structure-Property Prediction and Modeling Package

Simulations Plus Receives Multo-Year Pharmaceutical Software License
Large Pharmaceutical Company Renews Multi-year License