The chase is on to improve IVIVE approaches for compounds which are subject to complex absorption and clearance processes.
Using DDDPlus™ to Predict in vivo API Exposure Levels
There has been an increasing desire to incorporate mechanistic models of in vitro experiments to evaluate the interplay between...
Feature of the week #94: Individual parameters
Monolix estimates the population parameters, which characterize the population. But often we also need the parameter values for each individual present in the dataset.
Feature of the week #93: Initial integration time
When a model is defined as a system of differential equations, the initial integration time corresponding to the initial conditions of the system is not necessarily 0.
The GastroPlus® Additional Dosage Routes Seminar Series Discussion Panel
Ask Us Anything panel discussion
The GastroPlus® Additional Dosage Routes Seminar Series Ocular with Maxime Le Merdy
The Ocular Compartmental Absorption & Transit (OCAT™) model represents the eye as a collection of the following compartments...
The GastroPlus® Additional Dosage Routes Seminar Series IM with Viera Lukacova
The intramuscular (IM) drug delivery model represents the site of injection as a single compartment. Within this compartment...
The GastroPlus® Additional Dosage Routes Seminar Series Transdermal with Jessica Spires
The Transdermal Compartmental Absorption & Transit (TCAT™) model represents the skin as a collection...
The GastroPlus® Additional Dosage Routes Seminar Series Pulmonary with John DiBella and Jim Mullin
The Pulmonary Compartmental Absorption & Transit (PCAT™) model represents the lung/nose as a collection of the following...
Deployment of ADMET Predictor® as a Solution for In-Silico Modeling of ADMET Properties
David Miller, Director of ADMET Cheminformatics, will introduce how ADMET Predictor® is used as a platform for modeling ADMET Properties.
GastroPlus® “Workshop from Home” April 17 PBPK PD modeling course with Haiying Zhou
Advanced GastroPlus® DMPK & Clinical Pharmacology
GastroPlus® “Workshop from Home” April 16 Transporters in PBPK modeling with Ke Szeto
Advanced GastroPlus® DMPK & Clinical Pharmacology
GastroPlus® “Workshop from Home” April 15 DDI predictions with John DiBella
Advanced GastroPlus® DMPK & Clinical Pharmacology
GastroPlus® “Workshop from Home” April 14 Special population predictions with Viera Lukacova
Advanced GastroPlus® DMPK & Clinical Pharmacology
GastroPlus® “Workshop from Home” April 13 GastroPlus® Introduction with Maxime Le Merdy
Introductory GastroPlus® Simulation and Modeling
Live Stream Learning with Simulations Plus Day Two
Bringing you scientific talks & poster presentations you missed from the 59th Annual SOT/Tox Expo and American Society for Clinical Pharmacology & Therapeutics conference by Simulations Plus… virtually.
Early assessment of PK properties with the ADMET Predictor® HTPK Simulation module, a high-throughput mechanistic PBPK approach
This webinar introduces how the ADMET Predictor® HTPK Simulation module can effectively be used to provide early PK assessment in discovery programs.
Live Stream Learning with Simulations Plus: Day One
Bringing you scientific talks & poster presentations you missed from the 59th Annual SOT/Tox Expo and American Society for Clinical Pharmacology & Therapeutics conference by Simulations Plus… virtually.
Clinical DILI and State-of-the-Art Solutions
Translating in vitro safety data into quantitative risk assessment in specific patient populations remains a challenge.
Prediction of pH-Dependent Drug-Drug Interactions for Basic Drugs using PBBM Modeling: Industry Case Studies
Acid-reducing agents (ARA) such as antacids, histamine H2-receptor antagonists, and proton pump inhibitors are widely prescribed in several disease states.