This GastroPlus® webinar hosted by Joyce Macwan, Sr. Scientist II, provides an overview of mechanistic IVIVC and virtual bioequivalence trials to support formulation development.
The objectives of this complimentary lecture are to:
(1) Discuss differences between mechanistic and traditional deconvolution methods
(2) Share a case example to build and validate IVIVC using traditional (Loo-Riegelman) and mechanistic absorption deconvolution methods
(3) Discuss the synergy between DDDPlus™ and GastroPlus software
(4) Share a case example to determine dissolution specifications via virtual BE trials
BY Joyce Macwan, Viera Lukacova