The Transdermal Compartmental Absorption & Transit (TCAT™) model represents the skin as a collection of the following compartments: stratum corneum, viable epidermis, dermis, subcutaneous tissue, sebum, hair lipid, and hair core.
By Jessica Spires
- Software
- GastroPlus®
-
PBBM / PBPK modeling & simulation software package which simulates all major dosing routes and drug-drug interactions (DDIs) in virtual human & animal population groups.
-
- MonolixSuite™
-
Easy, fast, and powerful tool for parameter estimation in non-linear mixed effect models, model diagnosis and assessment, and advanced graphical representation.
-
- ADMET Predictor®
-
Flagship machine learning platform for ADMET modeling with extended capabilities for data analysis, metabolism prediction, high-throughput pharmacokinetic simulation (HTPK), and AI-driven drug design.
-
- DILIsym®
-
Quantitative Systems Toxicology (QST) software designed to be used during drug development to provide deeper insight into the mechanisms responsible for observed drug-induced liver injury (DILI) responses.
-
- DDDPlus™
-
A mechanistic simulation engine for the in vitro dissolution experiment that predicts in vitro disintegration and dissolution of pharmaceutical dosage forms.
-
- NAFLDsym®
-
Quantitative Systems Pharmacology (QSP) software for mechanistic mathematical modeling of nonalcoholic fatty liver disease (NAFLD.)
-
- MembranePlus™
-
A detailed modeling & simulation program for in vitro metabolism & transport studies.
-
- PKanalix™
-
Graphical and interactive software for non-compartmental and compartmental analysis.
-
- Simulx™
-
A powerful and flexible simulator for clinical trial pharmacometrics.
-
- IPFsym®
-
Quantitative Systems Pharmacology (QSP) software providing the ability to predict the efficacy of drugs being developed to treat idiopathic pulmonary fibrosis (IPF.)
-
- ILDsym™
-
Quantitative Systems Pharmacology (QSP) software for mechanistic mathematical modeling of interstitial lung disease (ILD) associated with system sclerosis (SSc.)
-
- RENAsym®
-
Quantitative Systems Toxicology (QST) software for predicting and understanding drug-induced kidney injury.
-
- MedChem Designer™
-
FREE chemical sketching software tool which combines innovative molecule drawing features.
-
- Custom QSP Software
-
Custom QSP software for predicting efficacy & guiding design.
-
- GastroPlus®
- Resource Center
Featured Webinar Replay
