Simulations Plus

Net sales increase to new record for any quarter of $2.789 million, up 24% sequentially and 6.4% compared to 2QFY11

Dr. David Ralph, Professor of Marketing at Pepperdine University, to Replace Dr. Richard Weiss, Retiring after Nearly 15 Years on Board

Board of directors declares an ongoing quarterly dividend of $0.05 per share

Net sales increase 9.6% to first quarter record $2.248 million; Net income up 30.9% to $755,000

Conference Call to be on Wednesday, January 18, at 4:15 PM ET

Fiscal Year Pharmaceutical Software and Services Up 14.7%, EPS Up 29.3%

Conference Call to be on Thursday, December 1, 2011 at 4:30 PM EST

Prentke Romich Company to Acquire Subsidiary and Continue Operations

Company Uses Proprietary Software Tools to Design New Drug-like Molecules for Resistant Malaria Parasite

Pharmaceutical Software and Services Revenues Increase 6.9% for 4th Quarter, up 14.7% for the Fiscal Year

In-house Design Widens Eye Gaze Offerings and Substantially Increases Margins

Record Quarterly Revenue of $3.44 Million; Consolidated Earnings Up 42% and EPS Up 49% from 3QFY10

Growth Trend Continues with Another Record Quarter

Conference Call to Be on Monday, April 18, at 4:15 PM EDT

Adds New MedChem Designer Molecule Drawing, Expanded Graphics, and More

String of Record Quarters Sustains Multi-Year Growth Trend

New Predictions Further Extend Best-in-Class Software

Powerful Molecule Drawing Tool Added to World-Class Product Line