Utilization of PBBM/PBPK Models for Building a Safe Space and Regulatory Applications in Support of Drug Product Quality

Utilization of PBBM/PBPK Models for Building a Safe Space and Regulatory Applications in Support of Drug Product Quality

Authors: Suarez-Sharp S
Software: GastroPlus®
Division: PBPK

Drug products undergo many chemistry, manufacturing, and control (CMC) changes throughout their lifecycle, making the overall process costly and time consuming.

DILIsym Simulations Support the Liver Safety of Ubrogepant in New Toxicological Sciences Publication

DILIsym Simulations Support the Liver Safety of Ubrogepant in New Toxicological Sciences Publication

Software: DILIsym®

Dr. Paul B. Watkins and Dr. Jeff Woodhead discuss the DILIsym analysis of the latest publication in Toxicological Sciences! Small-molecule calcitonin gene...

QSP/QST Modeling Support for NASH Drug Development

QSP/QST Modeling Support for NASH Drug Development

Authors: Siler SQ
Software: DILIsym®, NAFLDsym®

Quantitative Systems Pharmacology (QSP) Supports Clinical Development by Emphasizing Mechanistic Understanding of Pathophysiology and Treatment