Research Triangle Park, North Carolina
Scientific Advisory Committee on Alternative Toxicological Methods Meetings
This notice announces the next meeting of the Scientific Advisory Committee on Alternative Toxicological Methods (SACATM). SACATM, a federally chartered, external advisory group composed of scientists from the public and private sectors, including representatives of regulated industry and national animal protection organization, will review and provide advice on programmatic activities. SACATM advises the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), the National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), and the Director of the National Institute of Environmental Sciences (NIEHS) and NTP regarding statutorily mandated duties of ICCVAM and activites of NICEATM. The meeting is open to the public and registration is requested for both attendance and oral comment and required to access the webcast.View Event Details
Research Triangle Park, North Carolina
DILIsym® 2-Day Training Workshop
This two-day, hands-on course provides a working knowledge of the basic theories and application of state-of-the-art quantitative system toxicology (QST) modeling and simulation software (DILIsym®) for the analysis of the potential for drugs and drug candidates to cause drug-induced liver injury (DILI), or for the investigation of mechanisms involved in a documented DILI event.View Event Details
The European Quantitative Structure-Activity Relationships (EuroQSAR) Symposia are major scientific events that have been organized in different cities of Europe since 1973. They have the fascinating scope to promote and disseminate advances in rational approaches in drug design and discovery and ensure a worldwide attendance of prominent scientists from both academia and industry.
The 22nd EuroQSAR 2018 symposium, entitled “Translational and Health Informatics: Implications for Drug Discovery”, will take place September 16-20, 2018 in Thessaloniki, Greece. It is a Turkish-Greek co-organization and an EFMC sponsored event.
To honor his impact of his contributions in the field of computer-aided drug discovery (CADD) and QSAR, the 22 nd EuroQSAR Symposium is dedicated to the memory of Prof. Toshio Fujita (1929-2017).
Final IMI OrBiTo Meeting
The APS is pleased to announce this exciting 2 day meeting to review the progress and advances made by the collaborative IMI OrBiTo project . The OrBiTo project started in October 2012 and following a twelve-month non-cost extension phase will finish in October 2018.
The Innovative Medicines Initiative (IMI) ORBITO project is a pre-competitive collaboration between pharma, academia and specialist technology companies which aims to enhance our understanding of how orally-administered drugs are absorbed from the gastrointestinal tract and apply this knowledge to develop new in vitro tests and in silico models that will better predict the performance of oral formulations in patients (www.orbitoproject.eu).
The German Society for Rheumatology 46th Congress
At our congress, we want to provide a forum for this change. All those who deal with and live in rheumatology, scientifically, clinically or otherwise, should benefit from the experience of others and be actively involved in shaping our field of expertise. At the same time, the progress of other disciplines is valuable and instructive. The many intersections with orthopedics and orthopedic rheumatology and their focal point arthritis are important to us. In the preparation we want to include as many active designers of the next generation of rheumatologists and scientists.View Event Details
2018 ACCP Annual Meeting
This year’s meeting is focused on "Discovery & Innovation in Clinical Pharmacology: Application to Patient Care”. Consistent with ACCP’s commitment to excellence in science and education, the 2018 Annual Meeting Program Committee, co-chaired by Drs. Dionna Green and Amalia Issa, has worked diligently to provide a diverse and exceptional educational program that meets the needs of healthcare professionals and scientists with an interest in one or more of the myriad of applications of clinical pharmacology ranging from research and drug development to patient care. Speakers spanning the breadth of academia, industry, regulatory agencies, consulting companies and clinical specialties will present educational and scientific programs organized into topic tracks that allow attendees to uniquely tailor content selection to their individual interests.View Event Details
6th Biennial Conference on Resting State & Brain Connectivity
Following the successful previous conferences in Vienna (Austria, EU), Boston/Cambridge (Mass., USA), Magdeburg (Germany, EU), and Milwaukee (Wisc., USA), the Sixth Biennial Conference on Resting State and Brain Connectivity will take place in Montreal(Quebec, Canada) from September 26 to 28, 2018.View Event Details
Discovery on Target 2018
The 16th Annual Discovery on Target, “The Industry’s Preeminent Event on Novel Drug Targets,” will once again gather over 1,300 drug discovery professionals in Boston, MA, this September 25-28, 2018. The event brings forth current and emerging “hot” targets, technologies and validation strategies for the development of novel small molecules and biologics.View Event Details
ISSX Workshop on LC-MS Proteomics
For in vitro-in vivo extrapolation (IVIVE) of drug absorption, distribution, metabolism, excretion (ADME), pharmacodynamics (PD) and drug-drug interactions (DDI), quantitative systems pharmacology (QSP) models, including physiologically-based pharmacokinetic (PBPK) models, rely heavily on physiological parameters, such as the abundance of proteins in tissues important in these processes. A significant obstacle in quantification of the abundance of ADME and PD proteins is that conventional methods (e.g. Western blotting) cannot be used when purified standards of these proteins (e.g. transporters, receptors) are not available. Moreover, these conventional methods lack specificity, are low throughput and cumbersome. The advent of quantitative proteomics (QPr), based on LC-MS/MS, has overcome many of these disadvantages. Though this approach is increasingly being adopted by many laboratories, differences in its implementation have led to large differences in the reported abundance of ADME proteins.View Event Details
GastroPlus™ 2-Day Training Workshop
This 2-day hands-on course will provide an in-depth knowledge of the theories and application of state-of-the-art simulation and modeling software as it applies to problems facing pharmaceutical scientists dealing with drug product effects on dissolution, absorption and pharmacokinetics. Focus will be placed on applications of this technology as it relates to issues defined in the FDA’s Critical Path Initiative. A combination of presentations and interactive examples, taken from actual industry experience, will illustrate how to recognize and deal with the multiple interacting phenomena that affect the dissolution, absorption and pharmacokinetics of particular drugs, dosing routes, and dosage forms.View Event Details