02. Discover
What Is OBESITYsym?

OBESITYsym is a quantitative systems pharmacology (QSP) model that can help you predict… 

  • Drug efficacy for weight loss 
  • Range of weight loss to expect 
  • Probability of nausea side effects 
  • Dosing strategies that maximize weight loss and minimize nausea 
  • Range of patient variability 
  • Which patients are likely to develop tolerance 
  • Which patients should be monitored for down-titration for safety purposes 
  • And more 

OBESITYsym was developed and extensively validated with clinical data using our QSP modeling platform, Thales. It comes with SimPops, a feature that allows you to simulate the full range of clinical responses reported to date with the GLP-1 treatments currently available to obese patients, allowing you to predict outcomes for single and combination treatment strategies. It also allows you to explore mechanisms and modes of action for new treatments and compare novel compound performance against drugs already on the market, such as semaglutide, tirzepatide and liraglutide.  

And because OBESITYsym runs on the Thales modeling platform, you can feed in your existing clinical experience and data to optimize your predictions even further. 

03. Experts
Work With Our
QSP Experts

Need support? Our QSP modelers are highly experienced scientists who understand your program goals and are ready to help you meet them. 

How Others Are Using Our Tools
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