Reimagine the in vitro dissolution experiment…
Today, dissolution studies are the most frequently used tools in the development, characterization, and utilization process of pharmaceutical dosage forms, both immediate and controlled-release. As a formulation or CMC scientist, you’re often tasked with designing a product which achieves a target in vitro dissolution rate that will, hopefully, lead to desired in vivo exposure levels. Or, the lifecycle management team wants to assess the possibility of creating a once-a-day formulation which is bioequivalent to a B.I.D. (twice a day) or T.I.D. (three times a day) dosing regimen. You don’t have a lot of time or material available, so you begin manufacturing small lots of products to test under different conditions, hoping something works. What if there was a more efficient strategy?
Welcome to DDDPlus™, the industry’s leading mechanistic in vitro dissolution software for formulation and analytical scientists. With DDDPlus, you can model and simulate the in vitro dissolution of active pharmaceutical ingredients (API) and formulation excipients under various experimental conditions in seconds, and begin making informed decisions to help improve your chances for success.
To learn more on the development and use of DDDPlus™ software, register for our 2021 MIDD+ Scientific Conference on March 3rd and 4th.