Featured Webinars:

MembranePlus™ v2 webinar: Stimulate your kinetic understanding…

Use of oral absorption modelling to characterize drug release and absorption of a BCS II compound from IR formulations

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Unified dissolution / precipitation model and its use predicting absorption

3.3.16 - This webinar will focus on the description of a novel mechanistic mathematical model developed to describe in vitro dissolution and precipitation data and how the model can be used in a wider PBPK framework to explain complex absorption profiles for weak bases. gastroplus dddplus

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Application of Cellular Permeability Simulation and PBPK Models to Capture

12.10.15 - In this GastroPlus™ User Group webinar, we will discuss the validation of passive permeability estimates in MembranePlus™ based on molecular structure alone for a library of diverse compounds and how it compares to Kubinyi's drug partitioning theory. membraneplus gastroplus

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Applications of customized GastroPlus™ models

10.15.15. - This GastroPlus™ User Group video explores how the ACAT model, with customized refinement of the model parameters or design of the model structure, can provide valuable insights to address various aspects of challenges in biopharmaceutics, including PBPK modeling-based in vitro-in vivo correlations. gastroplus

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Analyzing the structural sensitivity of QSAR models using matched molecular

9.30.15 - This video explores analyzing the structural sensitivity of QSAR models using matched molecular pairs using MedChem Studio™. admet predictor medchem studio

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Applications and considerations of drug exposure predictions in pediatric

6.22.15 - This GastroPlus™ User Group webinar will focus on special considerations when performing pediatric PBPK modeling in GastroPlus™. gastroplus

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What’s New in ADMET Predictor™ 7.2?

6.10.15 - Two new models, fraction unbound to liver microsomes and unbound human liver microsomal intrinsic clearance, were added to ADMET Predictor 7.2. The CYP kinetic parameter models were also re-built. Incorporation of these models into GastroPlus is also discussed. Finally, the set up for our KNIME workflow is demonstrated. admet predictor

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What’s New In GastroPlus™ 9.0?

5.6.15 - This informative webinar covers the new features in the latest version of GastroPlus™ 9.0. gastroplus

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Human Exposure Predictions and Food Effect Risk Identification

3.19.15 - This GastroPlus™ User Group webinar explores human exposure predictions and food effect risk identification using preclinical data and PBPK models. gastroplus

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MembranePlus™ Webinar – Getting the Most out of Your In Vitro Permeability Studies

12.2.14 - In this video, Dr. Viera Lukacova discusses how to get the most out of your in vitro permeability assays with MembranePlus™. membraneplus

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Improving Bioavailability During Lead Optimization

10.16.14 - In this presentation, Dr. Eric Martin of Novartis discusses improving bioavailability during lead optimization using global sensitivity analysis (GSA) of physiologically based pharmacokinetics. admet predictor gastroplus

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