Géraldine Ayral
Géraldine Ayral, Ph.D.
VP Applications
Lixoft
About Géraldine
Dr Géraldine Ayral is a multidisciplinary scientist with a main interest in pharmacometrics.
She joined Lixoft in 2016 as VP Applications, where she is in charge of the support, the training, and the technical communication. Geraldine holds an engineering degree from Ecole Polytechnique (Paris, France) and a Master in computational biology from ETH Zürich (Switzerland) in 2012. After an experience as assistant project manager at SoBios, a start-up developing software for modeling and in silico simulation, she started a PhD in systems biology and multi-scale modeling at INRIA Paris. She received her doctoral degree in 2016.
Latest Research by Géraldine
Validation of non-compartmental analysis (NCA) and bioequivalence results of PKanalix with respect to Phoenix WinNonLin
Keywords: bioequivalence, compartmental analysis (CA), drug-drug interactions (DDIs), Food effects, noncompartmental analysis (NCA), pharmacokinetics, pkanalix featureSoftware: MonolixSuite™, Division: Lixoft
Using a population mechanistic TMDD model calibrated on preclinical monkey data to simulate first-in-human
Keywords: monolix, PKPD modeling, Pre-Clinical, simulx, SLP2021MIDDSoftware: MonolixSuite™, Simulx™Conference: SLP MIDD+Division: Lixoft
Simulx – GUI: a flexible and user-friendly application for simulations
Keywords: clinical trial, modeling and simulation, monolixsuite, simulxSoftware: Simulx™Conference: ACoPDivision: Lixoft
Simulation of first-in-human using an allometrically scaled population mechanistic TMDD model with preclinical monkey data
Keywords: first-in-human, PK data, simulx, TMDD modelSoftware: Simulx™Conference: ACoPDivision: Lixoft
Implementation of the C-QTc study using MonolixSuite applications
Keywords: concentration-QTc modelling, monolixsuite, QTcSoftware: MonolixSuite™Conference: ACoPDivision: Lixoft
A library of tumor growth and tumor growth inhibition models for the MonolixSuite
Keywords: monolixsuite, tumor growth, tumor growth inhibitionSoftware: MonolixSuite™Conference: ACoPDivision: Lixoft
Efficient Pharmacokinetic Modeling Workflow With the MonolixSuite: A Case Study of Remifentanil
Keywords: clinical trial simulations, model‐based drug development, monolix, pharmacokinetic (PK) modeling, PK, population PK modelSoftware: MonolixSuite™Division: LixoftPublication: CPT Pharmacometrics Syst Pharmacol