Géraldine Ayral

Géraldine Ayral

Géraldine Ayral, Ph.D.
VP Applications
Lixoft

About Géraldine
Dr Géraldine Ayral is a multidisciplinary scientist with a main interest in pharmacometrics.

She joined Lixoft in 2016 as VP Applications, where she is in charge of the support, the training, and the technical communication. Geraldine holds an engineering degree from Ecole Polytechnique (Paris, France) and a Master in computational biology from ETH Zürich (Switzerland) in 2012. After an experience as assistant project manager at SoBios, a start-up developing software for modeling and in silico simulation, she started a PhD in systems biology and multi-scale modeling at INRIA Paris. She received her doctoral degree in 2016.

Latest Research by Géraldine

11/30/2021

Validation of non-compartmental analysis (NCA) and bioequivalence results of PKanalix with respect to Phoenix WinNonLin

Pasquiers B, Gualano V, Twarogowska M, Ayral G

Keywords: bioequivalence, compartmental analysis (CA), drug-drug interactions (DDIs), Food effects, noncompartmental analysis (NCA), pharmacokinetics, pkanalix featureSoftware: MonolixSuite™, Division: Lixoft

Read More Click Here to View Share

04/28/2021

Modeling and Simulation of a parent-metabolite-PD datatset (Spring School challenge solution)

Ayral G

Keywords: clinical trial, Lixoft, monolix, Phase 1, simulxSoftware: MonolixSuite™, Simulx™Division: Lixoft

Read More Click Here to View Share

03/03/2021

Using a population mechanistic TMDD model calibrated on preclinical monkey data to simulate first-in-human

Ayral G

Keywords: monolix, PKPD modeling, Pre-Clinical, simulx, SLP2021MIDDSoftware: MonolixSuite™, Simulx™Conference: SLP MIDD+Division: Lixoft

Read More Click Here to View Share

11/12/2020

Simulx – GUI: a flexible and user-friendly application for simulations

Twarogowska M, Ayral G, Traynard P, Chauvin J

Keywords: clinical trial, modeling and simulation, monolixsuite, simulxSoftware: Simulx™Conference: ACoPDivision: Lixoft

Read More Click Here to View Share

11/10/2020

Simulation of first-in-human using an allometrically scaled population mechanistic TMDD model with preclinical monkey data

Ayral G, Traynard P, Twarogowska M

Keywords: first-in-human, PK data, simulx, TMDD modelSoftware: Simulx™Conference: ACoPDivision: Lixoft

Read More Click Here to View Share

11/10/2020

Implementation of the C-QTc study using MonolixSuite applications

Twarogowska M, Ayral G, Chauvin J, Traynard P

Keywords: concentration-QTc modelling, monolixsuite, QTcSoftware: MonolixSuite™Conference: ACoPDivision: Lixoft

Read More Click Here to View Share

11/10/2020

A library of tumor growth and tumor growth inhibition models for the MonolixSuite

Traynard P, Ayral G, Twarogowska M

Keywords: monolixsuite, tumor growth, tumor growth inhibitionSoftware: MonolixSuite™Conference: ACoPDivision: Lixoft

Read More Click Here to View Share

02/09/2020

Efficient Pharmacokinetic Modeling Workflow With the MonolixSuite: A Case Study of Remifentanil

Traynard P, Ayral G, Twarogowska M, Chauvin J

Keywords: clinical trial simulations, model‐based drug development, monolix, pharmacokinetic (PK) modeling, PK, population PK modelSoftware: MonolixSuite™Division: LixoftPublication: CPT Pharmacometrics Syst Pharmacol

Read More Click Here to View Share