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        PBBM/PBPK
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        PBBM / PBPK modeling & simulation software package which simulates all major dosing routes and drug-drug interactions (DDIs) in virtual human & animal population groups.

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        PK/PD
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        Easy, fast, and powerful tool for parameter estimation in non-linear mixed effect models, model diagnosis and assessment, and advanced graphical representation.

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    • ADMET Predictor®
      • ADMET Predictor®
        ADMET Predictor®
        ADMET/ML
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        Flagship machine learning platform for ADMET modeling with extended capabilities for data analysis, metabolism prediction, high-throughput pharmacokinetic simulation (HTPK), and AI-driven drug design.

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        Quantitative Systems Toxicology (QST) software designed to be used during drug development to provide deeper insight into the mechanisms responsible for observed drug-induced liver injury (DILI) responses.

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        PBBM/PBPK
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        A mechanistic simulation engine for the in vitro dissolution experiment that predicts in vitro disintegration and dissolution of pharmaceutical dosage forms.

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      • NAFLDsym®
        NAFLDsym®
        QSP
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        Quantitative Systems Pharmacology (QSP) software for mechanistic mathematical modeling of nonalcoholic fatty liver disease (NAFLD.)

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        MembranePlus™
        PBBM/PBPK
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        A detailed modeling & simulation program for in vitro metabolism & transport studies.

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        PK/PD
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        Graphical and interactive software for non-compartmental and compartmental analysis.

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        Simulx™
        PK/PD
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        A powerful and flexible simulator for clinical trial pharmacometrics.

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      • IPFsym®
        IPFsym®
        QSP
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        IPFsym®

        Quantitative Systems Pharmacology (QSP) software providing the ability to predict the efficacy of drugs being developed to treat idiopathic pulmonary fibrosis (IPF.)

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      • ILDsym™
        ILDsym™
        QSP
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        ILDsym™

        Quantitative Systems Pharmacology (QSP) software for mechanistic mathematical modeling of interstitial lung disease (ILD) associated with system sclerosis (SSc.)

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      • RENAsym®
        RENAsym®
        QST
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        RENAsym®

        Quantitative Systems Toxicology (QST) software for predicting and understanding drug-induced kidney injury.

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        • RENAsym, a QST Model to Predict Drug-Induced Kidney Injury
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      • MedChem Designer™
        MedChem Designer™
        ADMET/ML
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        MedChem Designer™

        FREE chemical sketching software tool which combines innovative molecule drawing features.

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Consult + Coach
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Consult + Coach
  • January 20, 2023
  • Flyers

Consult + Coach

Keywords: consult & coach, gastroplus, Modeling and simulations, monolix, PBPK modeling
Software: GastroPlus®, Monolix®
Division: Lixoft, Simulations Plus

Accelerate Your Program and Invest in Your Future

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Resident Clinical Pharmacology Services
  • December 15, 2021
  • Flyers

Resident Clinical Pharmacology Services

Keywords: clinical pharmacology, cognigen consulting, pharmacology, pharmacometrics
Division: Cognigen

Our consultants are committed to providing you with the highest level of service, meeting your timelines and providing the highest quality quantitative support you can find.

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QSP/QST Capabilities Flyer
  • December 3, 2021
  • Flyers

QSP/QST Capabilities Flyer

Keywords: fit-for-purpose (F4P) models, idiopathic pulmonary fibrosis, non-alcoholic steatohepatitis (NASH), qsp, QST, quantitative systems pharmacology (QSP), Quantitative Systems Toxicology (QST)
Software: DILIsym®, IPFsym®, NAFLDsym®, RENAsym®

QSP/QST Services from the DILIsym Services division of Simulations Plus

  • Read More
  • Click to View
Internship+ Flyer
  • December 2, 2021
  • Flyers

Internship+ Flyer

Keywords: internship, Software, University+ Program
Division: Simulations Plus

Opportunities to apply model informed drug development (MIDD) skills and methods with Simulations Plus.

  • Read More
  • Click to View
QSP/QST Services from the DILIsym Services division of Simulations Plus
  • October 29, 2021
  • Flyers

QSP/QST Services from the DILIsym Services division of Simulations Plus

Keywords: custom QSP, DILIsym, QSP modeling, QST modeling
Software: DILIsym®, ILDsym™, IPFsym®, NAFLDsym®, RENAsym®
Division: DILIsym Services
  • Read More
  • Click to View
Noncompartmental PK/TK Analysis
  • October 1, 2021
  • Flyers

Noncompartmental PK/TK Analysis

Keywords: noncompartmental analysis (NCA), pharmacometrics pk analysis, pk/tk, preclinical pharmacokinetics, preclinical toxicokinetics
Division: Cognigen

Cognigen has a long-standing reputation for accuracy and integrity in providing noncompartmental analysis in a validated environment with submission-ready report.

  • Read More
  • Click to View
Cognigen Flyer
  • September 16, 2021
  • Flyers

Cognigen Flyer

Keywords: clinical trial simulations, PBPK modeling, pharmacometrics, PK/PD modeling, statistical modeling
Division: Cognigen

Cognigen uses the tools of pharmacometrics, embedded in a highly developed enterprise infrastructure, to support decision-making at critical points...

  • Read More
  • Click to View
StrategiesPlus™ Flyer
  • February 2, 2021
  • Flyers

StrategiesPlus™ Flyer

Keywords: regulatory support, Strategies+, StrategiesPlus™
Division: Simulations Plus

Regulatory Strategy & Support

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DILI-sim Initiative
  • December 3, 2020
  • Flyers

DILI-sim Initiative

Keywords: DILI-sim, DILI-sim Initiative, drug-induced liver injury
Division: DILIsym Services

Consortium distributing and developing software for predicting and preventing drug-induced liver injury

  • Read More
  • Click to View
PBPK… Meet Drug Design
  • September 1, 2020
  • Flyers

PBPK… Meet Drug Design

Keywords: admet predictor, AIDD, ddI, gastroplus, machine learning, PBPK modeling
Software: ADMET Predictor®, GastroPlus®
Division: Simulations Plus
  • Read More
  • Click to View
StrategiesPlus™ with Dr. Sandra Suarez-Sharp
  • March 18, 2020
  • Flyers

StrategiesPlus™ with Dr. Sandra Suarez-Sharp

Keywords: FDA, regulatory, regulatory assessment
Division: Simulations Plus

Our goal is to help our clients minimize or eliminate the questions posed by regulatory reviews while decreasing the cost and time it takes to develop detailed reports.

  • Read More
  • Click to View
GAP Flyer
  • August 22, 2019
  • Flyers

GAP Flyer

Keywords: ADMET Modeler, drug development, drug discovery, generic drug chemistry, PBPK modeling
Software: ADMET Predictor®, GastroPlus®
Division: Simulations Plus

Synchronize discovery and development ADME

  • Read More
  • Click to View
Upcoming Workshops
  • July 19, 2019
  • Flyers

Upcoming Workshops

Keywords: chemical and drug induced liver injury, machine learning, mechanistic absorption modeling, PBMM, PBPK, PBPK modeling and simulation workshop, PK/PD modeling, population PK data analysis workshop, qsp, workshops
Software: DILIsym®, GastroPlus®, KIWI™
Division: Simulations Plus

Here are few upcoming workshops.

  • Read More
  • Click to View
Harnessing the Power of Data Assembly for Pharmacometric Analysis
  • February 13, 2018
  • Flyers

Harnessing the Power of Data Assembly for Pharmacometric Analysis

Division: Cognigen

The lead time required for development of population pharmacokinetic (PK) and pharmacodynamic (PD) models places enormous pressure on data programming to expedite the transformation of disparate data into an analysis-ready dataset.

  • Read More
  • Click to View
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