GastroPlus User Group - Simulations Plus

This Month In GastroPlus® Modeling

Watch Webinar Replay

View Publication

Stay up-to-date with conferences, scientific talks, webinars, workshops, and more.

Redwood City, CA
February 25- March 1, 2019

Register for a workshop

With over 1,000 members and growing…interact with your peers around the globe!*

How well does GP predict brain PK in mice and more specifically in mdr1 -/- mice? Can rate of entry be predicted?

Food Effect Projections via Physiologically Based Pharmacokinetic Modeling: Predictive Case Studies

Question on simulation of re-dissolution of precipitated drug particles in GI tract

*note: must sign into LinkedIn and be a member of the GastroPlus User Group to review and contribute

New peer-reviewed journal publications citing various applications of GastroPlus software.Physiologically Based Absorption Modeling to Predict Bioequivalence of Controlled Release and Immediate Release Oral Products.Application of a Dynamic Fluid & pH Model to Simulate Intraluminal and Systemic Concentrations of a Weak Base in GastroPlus™.Integration of Precipitation Kinetics From an In vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs.Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA).Prediction of ARA/PPI Drug-Drug Interactions at the Drug Discovery and Development Interface.