Case study: Inter-occasion variability and effect of guar gum on alcohol concentration in blood

Software: Monolix®
Division: Lixoft

In this case study, the MonolixSuite is used to analyze and model the PK of alcohol, measured in two different occasions where subjects have taken or not a dietary additive of guar gum. The case study focuses in particular on the modeling of inter-occasion variability and the effect of guar gum on the bioavailability. Several applications of the MonolixSuite are used: Datxplore for data exploration, PKanalix for NCA and CA, Monolix for population modeling, and Sycomore to compare several Monolix runs.