Concentration Profiles of Carvedilol: A Comparison Between In Vitro Transfer Model and Dissolution Testing

Authors: Hamed R, Kamal A
Publication: J Pharma Innovation
Software: GastroPlus®


The study aims to investigate the transfer behavior of the weakly basic BCS class II model drug carvedilol from the stomach to the small intestine and compare the concentration profiles of carvedilol that were determined during the in vitro transfer model and dissolution testing.